Name: | Apolipoprotein E4 |
---|---|
Description: | A major and the second most common isoform of apolipoprotein E. In humans, Apo E4 differs from APOLIPOPROTEIN E3 at only one residue 112 (cysteine is replaced by arginine), and exhibits a lower resistance to denaturation and greater propensity to form folded intermediates. Apo E4 is a risk factor for ALZHEIMER DISEASE and CARDIOVASCULAR DISEASES. |
Synonyms: |
Apolipoprotein E-4; Apolipoprotein E 4; Apo E-4; Apo E epsilon 4; Apo E 4; Apo E4; ApoE4
|