Name: | Antigens, CD86 |
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Description: | A costimulatory ligand expressed by ANTIGEN-PRESENTING CELLS that binds to CD28 ANTIGEN with high specificity and to CTLA-4 ANTIGEN with low specificity. The interaction of CD86 with CD28 ANTIGEN provides a stimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE. |
Synonyms: |
B7-2 Antigen; Antigen, B7-2; Costimulatory Molecule, B70; Antigen, B7 2; Costimulatory Molecule, B7-2; B70 Costimulatory Molecule; CD86 Antigens; B7-2 Costimulatory Molecule; Early T Cell Costimulatory Molecule 1; B7 2 Antigen.
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