QuickView for bmp4 (gene)

GO Molecular Function

transforming growth factor beta receptor binding | signaling receptor binding | carbohydrate derivative binding | cytokine receptor binding | receptor serine/threonine kinase binding | molecular function regulator | anion binding | co-receptor binding | ion binding | heparin binding | protein binding | receptor regulator activity | growth factor activity | receptor ligand activity | cytokine activity | chemoattractant activity | glycosaminoglycan binding | BMP receptor binding

GO Biological Process

negative regulation of lymphocyte differentiation | negative regulation of leukocyte activation | positive regulation of smooth muscle cell proliferation | regulation of ERK1 and ERK2 cascade | negative regulation of phosphorylation | brain development | limb development | pulmonary artery endothelial tube morphogenesis | positive regulation of striated muscle cell differentiation | SMAD protein signal transduction | regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | regulation of intracellular protein transport | negative regulation of MAPK cascade | negative regulation of immune system process | negative regulation of embryonic development | apoptotic process involved in endocardial cushion morphogenesis | pharyngeal system development | regulation of neurogenesis | cranial skeletal system development | developmental process involved in reproduction | regulation of cellular localization | muscle tissue development | negative regulation of glomerular mesangial cell proliferation | positive regulation of apoptotic process | regulation of cell development | regulation of localization | positive regulation of collagen metabolic process | morphogenesis of an epithelium | cell proliferation involved in kidney development | positive regulation of striated muscle tissue development | regulation of programmed cell death | regulation of cardiac muscle cell differentiation | erythrocyte homeostasis | eye development | smooth muscle cell differentiation | embryonic skeletal joint morphogenesis | regulation of immune system process | response to hormone | myeloid cell differentiation | regulation of immature T cell proliferation in thymus | positive regulation of cardiac muscle fiber development | negative regulation of cellular process | negative regulation of kinase activity | negative regulation of leukocyte cell-cell adhesion | neural tube patterning | positive regulation of developmental process | regulation of MAP kinase activity | negative regulation of RNA biosynthetic process | embryonic appendage morphogenesis | bone development | regulation of protein import | cell differentiation | positive regulation of epithelial cell proliferation | regulation of T cell differentiation | respiratory tube development | glomerulus development | nervous system development | epithelial to mesenchymal transition | type B pancreatic cell differentiation | negative regulation of protein phosphorylation | positive regulation of biomineral tissue development | endochondral bone morphogenesis | neurogenesis | pulmonary valve development | epithelial to mesenchymal transition involved in endocardial cushion formation | positive regulation of phosphate metabolic process | negative regulation of cell proliferation involved in kidney development | regulation of organelle organization | positive regulation of endothelial cell proliferation | positive regulation of cellular component movement | generation of neurons | mesenchyme development | telencephalon regionalization | hormone-mediated signaling pathway | blood vessel morphogenesis | pattern specification process | regulation of branch elongation involved in ureteric bud branching | negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway | positive regulation of cellular biosynthetic process | cellular process | muscular septum morphogenesis | regulation of branching involved in prostate gland morphogenesis | negative regulation of muscle organ development | regulation of production of miRNAs involved in gene silencing by miRNA | positive regulation of cartilage development | regulation of cell motility | localization | epithelial tube morphogenesis | limb morphogenesis | mesoderm morphogenesis | odontogenesis | lymphoid progenitor cell differentiation | heart morphogenesis | type B pancreatic cell development | negative regulation of signaling | developmental growth | cranial suture morphogenesis | negative regulation of developmental growth | reproductive system development | negative regulation of metanephric S-shaped body morphogenesis | positive regulation of epithelial to mesenchymal transition | mesoderm development | regulation of mitotic nuclear division | regulation of embryonic development | positive regulation of pathway-restricted SMAD protein phosphorylation | immune system development | multicellular organismal reproductive process | negative regulation of nucleic acid-templated transcription | negative regulation of mesenchymal cell proliferation | renal tubule morphogenesis | regulation of striated muscle tissue development | positive regulation of protein kinase activity | macromolecule localization | bronchus development | glandular epithelial cell differentiation | negative regulation of apoptotic process | branching involved in ureteric bud morphogenesis | digestive tract morphogenesis | glomerular visceral epithelial cell development | regulation of cell cycle | response to growth factor | positive regulation of catalytic activity | lung epithelium development | positive regulation of nitrogen compound metabolic process | negative regulation of T cell proliferation | diencephalon development | endothelial cell proliferation | positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis | negative regulation of cellular metabolic process | regulation of bone mineralization | tissue development | regulation of binding | regulation of cell differentiation | gamete generation | positive regulation of endothelial cell differentiation | metanephric nephron development | apoptotic process involved in heart morphogenesis | positive regulation of muscle cell differentiation | muscle structure development | muscle cell differentiation | ventricular septum morphogenesis | hindlimb morphogenesis | regulation of lymphocyte apoptotic process | negative regulation of apoptotic signaling pathway | regulation of cellular process | regulation of osteoblast differentiation | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | pituitary gland development | regulation of odontogenesis of dentin-containing tooth | metanephric nephron morphogenesis | negative regulation of mononuclear cell proliferation | deltoid tuberosity development | negative regulation of cell proliferation involved in heart morphogenesis | positive regulation of cellular protein metabolic process | regulation of neural crest cell differentiation | epithelium development | regulation of gene silencing by miRNA | endocrine pancreas development | prostate gland epithelium morphogenesis | epithelial tube branching involved in lung morphogenesis | urogenital system development | positive regulation of protein binding | positive regulation of epithelial cell migration | mammary gland morphogenesis | nephron tubule morphogenesis | head development | sprouting angiogenesis | muscle organ morphogenesis | regulation of vasculature development | response to stimulus | cardiac right ventricle morphogenesis | vasculature development | regulation of cellular protein localization | negative regulation of T cell apoptotic process | embryonic limb morphogenesis | nephric duct morphogenesis | respiratory system development | collecting duct development | embryonic epithelial tube formation | positive regulation of protein metabolic process | negative regulation of cell adhesion | bud dilation involved in lung branching | mesoderm formation | gland morphogenesis | regulation of SMAD protein signal transduction | positive regulation of epidermal cell differentiation | negative regulation of lymphocyte activation | germ cell development | negative regulation of protein kinase activity | craniofacial suture morphogenesis | regulation of cell proliferation | specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway | tube morphogenesis | cardiac muscle tissue development | protein localization to nucleus | muscle tissue morphogenesis | epithelial cell development | hematopoietic progenitor cell differentiation | regulation of epithelial cell differentiation | cloaca development | programmed cell death | forebrain regionalization | epithelial tube formation | mesodermal cell fate determination | reproduction | cellular localization | embryonic skeletal system development | cardiovascular system development | regulation of glomerular mesangial cell proliferation | cardiac ventricle morphogenesis | heart formation | regulation of gene silencing | macrophage differentiation | axis elongation | inner ear receptor cell differentiation | cellular response to organic cyclic compound | metanephros morphogenesis | negative regulation of muscle tissue development | regulation of protein transport | negative regulation of metabolic process | positive regulation of BMP signaling pathway | positive regulation of protein serine/threonine kinase activity | positive regulation of RNA biosynthetic process | hemopoiesis | negative regulation of hemopoiesis | ureter urothelium development | protein modification process | steroid hormone mediated signaling pathway | regulation of odontogenesis | cartilage development | regulation of peptide transport | tendon cell differentiation | negative regulation of immature T cell proliferation | regulation of cell adhesion | dorsal/ventral pattern formation | kidney development | embryo development | regulation of morphogenesis of a branching structure | regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis | macromolecule modification | cell-cell signaling | trachea morphogenesis | BMP signaling pathway involved in ureter morphogenesis | activation of protein kinase activity | positive regulation of production of miRNAs involved in gene silencing by miRNA | mammary gland formation | regulation of intracellular transport | molecular function regulator | cell surface receptor signaling pathway involved in cell-cell signaling | positive chemotaxis | regulation of lymphocyte differentiation | blood vessel development | myeloid cell homeostasis | anterior/posterior pattern specification | pulmonary valve morphogenesis | neuron fate commitment | regulation of nucleic acid-templated transcription | leukocyte differentiation | locomotion | lung alveolus development | response to BMP | apoptotic process | embryonic skeletal joint development | cellular response to hormone stimulus | negative regulation of mesenchymal cell proliferation involved in ureter development | endocardial cushion development | system development | chondrocyte differentiation | nitrogen compound metabolic process | enteroendocrine cell differentiation | reproductive process | regulation of signal transduction | endothelium development | ureteric bud development | negative regulation of growth | negative regulation of phosphate metabolic process | regulation of cartilage development | multicellular organism development | negative regulation of catalytic activity | BMP signaling pathway involved in nephric duct formation | glomerulus vasculature development | intermediate mesodermal cell differentiation | regulation of MAPK cascade | regulation of BMP signaling pathway | phosphorus metabolic process | regulation of collagen biosynthetic process | negative regulation of glomerulus development | mammary gland development | positive regulation of muscle organ development | blood vessel endothelial cell proliferation involved in sprouting angiogenesis | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | kidney morphogenesis | regulation of ossification | positive regulation of cell proliferation involved in outflow tract morphogenesis | mechanoreceptor differentiation | cardiac epithelial to mesenchymal transition | monocyte differentiation | regulation of T cell activation | telencephalon development | artery development | cloacal septation | regulation of neuron differentiation | regulation of gene expression | regulation of extrinsic apoptotic signaling pathway | kidney epithelium development | pancreas development | neural tube closure | mesenchymal cell differentiation involved in kidney development | outflow tract morphogenesis | response to lipid | endocardial cushion morphogenesis | regulation of epidermis development | branching involved in prostate gland morphogenesis | negative regulation of metanephric comma-shaped body morphogenesis | myeloid leukocyte differentiation | coronary vasculature development | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | epithelial-mesenchymal cell signaling | regulation of lymphocyte activation | regulation of smooth muscle cell differentiation | animal organ morphogenesis | regulation of pri-miRNA transcription by RNA polymerase II | regulation of protein localization to nucleus | negative regulation of chondrocyte differentiation | specification of animal organ identity | negative regulation of lymphocyte apoptotic process | regulation of nitrogen compound metabolic process | negative regulation of T cell activation | regulation of cell migration | cardiac jelly development | enzyme linked receptor protein signaling pathway | positive regulation of intracellular signal transduction | neural tube formation | cardiocyte differentiation | negative regulation of protein serine/threonine kinase activity | regulation of branching involved in lung morphogenesis | regulation of cellular component movement | regulation of transcription by RNA polymerase II | endochondral ossification | epithelial cell proliferation involved in lung morphogenesis | protein localization to organelle | negative regulation of myoblast differentiation | positive regulation of cell differentiation | regulation of endothelial cell migration | negative regulation of mitotic nuclear division | negative regulation of extrinsic apoptotic signaling pathway | homeostasis of number of cells | renal vesicle morphogenesis | negative regulation of immature T cell proliferation in thymus | positive regulation of cell migration | regulation of cell proliferation involved in heart morphogenesis | cell proliferation | pharyngeal arch artery morphogenesis | aortic valve morphogenesis | neural tube development | regulation of cellular protein metabolic process | cell differentiation involved in kidney development | positive regulation of SMAD protein signal transduction | positive regulation of ossification | angiogenesis | mesenchyme morphogenesis | phosphorylation | mesonephric epithelium development | cardiac septum morphogenesis | digestive tract development | nephric duct formation | glandular epithelial cell development | mesenchymal to epithelial transition involved in metanephros morphogenesis | BMP signaling pathway involved in heart induction | glomerulus morphogenesis | regulation of apoptotic signaling pathway | endocrine system development | protein phosphorylation | bud elongation involved in lung branching | mesonephros development | post-embryonic development | mesenchymal to epithelial transition | phosphate-containing compound metabolic process | sensory organ development | mesenchymal cell proliferation involved in ureteric bud development | mesodermal cell fate commitment | trachea formation | ureter smooth muscle cell differentiation | negative regulation of cell-cell adhesion | chordate embryonic development | animal organ formation | striated muscle tissue development | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | eye morphogenesis | transmembrane receptor protein serine/threonine kinase signaling pathway | tendon formation | skeletal system morphogenesis | metanephros development | anterior/posterior axis specification | renal tubule development | cell differentiation involved in metanephros development | semi-lunar valve development | odontogenesis of dentin-containing tooth | nephric duct development | negative regulation of cell activation | regulation of T cell apoptotic process | activation of MAPKK activity | regulation of collagen metabolic process | regulation of protein metabolic process | dorsal/ventral neural tube patterning | positive regulation of signal transduction | inner ear development | glomerular capillary formation | negative regulation of striated muscle tissue development | heart development | apoptotic process involved in development | homeostatic process | positive regulation of cell proliferation | regulation of protein phosphorylation | bone morphogenesis | regulation of locomotion | embryo development ending in birth or egg hatching | negative regulation of MAP kinase activity | regulation of RNA metabolic process | regulation of stem cell differentiation | renal system development | common-partner SMAD protein phosphorylation | striated muscle cell differentiation | regulation of cellular response to growth factor stimulus | embryonic hindlimb morphogenesis | embryonic morphogenesis | negative regulation of T cell differentiation | regulation of mitotic cell cycle | nephron development | smooth muscle tissue development | glomerular visceral epithelial cell differentiation | positive regulation of molecular function | regulation of nucleocytoplasmic transport | positive regulation of osteoblast differentiation | negative regulation of thymocyte apoptotic process | neuron differentiation | multicellular organism reproduction | embryonic organ morphogenesis | embryonic cranial skeleton morphogenesis | regulation of signaling receptor activity | receptor regulator activity | negative regulation of branching involved in ureteric bud morphogenesis | ureteric bud morphogenesis | heart valve development | ventricular septum development | negative regulation of epithelial cell proliferation | protein metabolic process | regulation of establishment of protein localization | regionalization | cardiac ventricle development | axis specification | positive regulation of protein modification process | regulation of growth | response to organic substance | gland development | regulation of cardiac muscle tissue development | lens morphogenesis in camera-type eye | tissue morphogenesis | artery morphogenesis | regulation of protein import into nucleus | digestive system development | regulation of hemopoiesis | regulation of prostatic bud formation | branching morphogenesis of an epithelial tube | epithelial cell proliferation | regulation of kinase activity | regulation of animal organ morphogenesis | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | specification of animal organ position | anatomical structure development | developmental growth involved in morphogenesis | branch elongation of an epithelium | cell surface receptor signaling pathway | positive regulation of neurogenesis | metanephric renal vesicle morphogenesis | growth factor activity | embryonic skeletal system morphogenesis | endothelial tube morphogenesis | metabolic process | metanephric collecting duct development | positive regulation of cell development | cell fate commitment | mesenchymal cell differentiation | ureter morphogenesis | regulation of thymocyte apoptotic process | negative regulation of leukocyte proliferation | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | negative regulation of programmed cell death | embryonic organ development | regulation of myoblast differentiation | negative regulation of mitotic cell cycle | cellular protein localization | ear development | positive regulation of cell death | heart field specification | trachea development | regulation of gene silencing by RNA | morphogenesis of embryonic epithelium | receptor ligand activity | regulation of chondrocyte differentiation | mesenchymal cell proliferation | cytokine activity | heart valve morphogenesis | organic substance metabolic process | connective tissue development | cell death | negative regulation of biosynthetic process | chemoattractant activity | negative regulation of gene expression | nephron morphogenesis | animal organ development | regulation of endothelial cell proliferation | forebrain development | negative regulation of cellular protein metabolic process | regulation of cell activation | positive regulation of ERK1 and ERK2 cascade | positive regulation of programmed cell death | positive regulation of kinase activity | positive regulation of branching involved in lung morphogenesis | regulation of heart morphogenesis | regulation of striated muscle cell differentiation | regulation of phosphate metabolic process | cellular response to steroid hormone stimulus | prostate gland morphogenesis | renal system process | positive regulation of binding | BMP signaling pathway involved in heart development | positive regulation of muscle tissue development | positive regulation of endothelial cell migration | positive regulation of stem cell differentiation | positive regulation of MAPK cascade | lung development | morphogenesis of a branching epithelium | intermediate mesoderm development | ureter epithelial cell differentiation | camera-type eye development | pulmonary artery morphogenesis | smoothened signaling pathway | anatomical structure formation involved in morphogenesis | negative regulation of cartilage development | negative regulation of cell cycle | negative regulation of protein metabolic process | regulation of epithelial cell migration | regulation of animal organ formation | positive regulation of cardiac muscle cell differentiation | BMP signaling pathway involved in renal system segmentation | cardiac muscle cell differentiation | BMP signaling pathway | positive regulation of cell proliferation involved in heart morphogenesis | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | signaling | regulation of transcription, DNA-templated | regulation of protein binding | response to organic cyclic compound | cell development | embryonic digit morphogenesis | regulation of developmental growth | regulation of T cell proliferation | protein localization | regulation of epithelial cell proliferation | regulation of production of small RNA involved in gene silencing by RNA | negative regulation of leukocyte apoptotic process | regulation of T cell differentiation in thymus | positive regulation of phosphorylation | cellular protein metabolic process | endocardial cushion formation | endoderm development | morphogenesis of a branching structure | anatomical structure morphogenesis | prostate gland development | cellular macromolecule localization | cell fate commitment involved in formation of primary germ layer | camera-type eye morphogenesis | positive regulation of MAP kinase activity | reproductive structure development | regulation of nervous system development | positive regulation of gene silencing by miRNA | regulation of developmental process | renal vesicle development | segmentation | regulation of mesenchymal cell proliferation | developmental process | ureter development | regulation of muscle cell differentiation | erythrocyte differentiation | cardiac septum development | cellular protein modification process | positive regulation of epithelial cell differentiation | columnar/cuboidal epithelial cell development | negative regulation of transcription by RNA polymerase II | tube development | regulation of transport | positive regulation of transcription, DNA-templated | aortic valve development | membranous septum morphogenesis | negative regulation of cell proliferation | regulation of cell-cell adhesion | negative regulation of vasculature development | negative regulation of prostatic bud formation | regulation of endothelial cell differentiation | positive regulation of kidney development | positive regulation of nucleic acid-templated transcription | cell fate determination | tendon development | lung morphogenesis | tube closure | epithelial cell differentiation | formation of primary germ layer | positive regulation of transcription by RNA polymerase II | regulation of epithelial to mesenchymal transition | positive regulation of epidermis development | secondary heart field specification | cardiac chamber development | tube formation | regulation of branching involved in ureteric bud morphogenesis | regulation of cell fate commitment | central nervous system development | mesodermal cell differentiation | positive regulation of metabolic process | ossification | positive regulation of neuron differentiation | cellular response to BMP stimulus | organ induction | osteoblast differentiation | apoptotic process involved in morphogenesis | skeletal system development | negative regulation of lymphocyte proliferation | gastrulation | immune system process | positive regulation of collagen biosynthetic process | cellular metabolic process | hematopoietic or lymphoid organ development | negative regulation of cell cycle process | cellular response to organic substance | regulation of protein localization | regulation of transcription from RNA polymerase II promoter involved in kidney development | regulation of cell death | positive regulation of cardiac muscle tissue development | regulation of smooth muscle cell proliferation | positive regulation of cell motility | response to steroid hormone | mesenchymal cell proliferation involved in ureter development | negative regulation of cell death | developmental induction | circulatory system development | chemotaxis | glomerular epithelium development | negative regulation of T cell differentiation in thymus | mesenchymal cell differentiation involved in renal system development | sexual reproduction | negative regulation of pri-miRNA transcription by RNA polymerase II | nephron tubule development | negative regulation of cell differentiation | regulation of cellular component organization | positive regulation of bone mineralization | regulation of epidermal cell differentiation | lens development in camera-type eye | lens induction in camera-type eye | muscle organ development | positive regulation of signaling | signal transduction | regulation of signaling | mesonephric tubule development | regulation of pathway-restricted SMAD protein phosphorylation | positive regulation of gene expression | post-translational protein modification | outflow tract septum morphogenesis | cellular response to growth factor stimulus | regulation of muscle organ development | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | endomembrane system | endoplasmic reticulum lumen | extracellular region | membrane-bounded organelle | organelle | extracellular space | membrane-enclosed lumen | intracellular

PATHWAYS

PID_BMP_PATHWAY | NABA_SECRETED_FACTORS | NABA_MATRISOME | NABA_MATRISOME_ASSOCIATED

PROTEIN FAMILY

TGF-beta, propeptide | Transforming growth factor-beta, C-terminal | Transforming growth factor-beta-related | Transforming growth factor beta, conserved site | Cystine-knot cytokine