Correlation Engine 2.0
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QuickView for bsh3;jsessionid=99AD8C217BF2DE5F13C4405EBE02894C;jsessionid=E82EBFBFC07E605CAB674019FD1A5EF4;jsessionid=1CFD8820A90B14FF1C2CCA5E2A9D364A (gene)


Gene Symbol:
GINS2 Homo sapiens Homo sapiens
Full name:
GINS complex subunit 2
Synonyms:
HSPC037, PSF2, Pfs2, DNA replication complex GINS protein PSF2, GINS complex subunit 2 (Psf2 homolog)
Genomic Location:
Chr 16: 84268781-84280081
Description:
The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1 (GINS1; MIM 610608), Psf2, and Psf3 (GINS3; MIM 610610). The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS co...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Pan troglodytes Danio rerio Canis lupus familiaris
External Links:
Entrez Gene
Cytogenetic Map:
chr 16
16q24.1


Transcripts Names
NM_016095
Protein Names
D3DUM5
Q9Y248
Q6IAG9



GO Molecular Function

3'-5' DNA helicase activity | hydrolase activity | pyrophosphatase activity | catalytic activity | nucleoside-triphosphatase activity | DNA helicase activity | protein binding | hydrolase activity, acting on acid anhydrides | helicase activity | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

GO Biological Process

double-strand break repair | cellular process | double-strand break repair via break-induced replication | 3'-5' DNA helicase activity | DNA geometric change | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | DNA-dependent DNA replication | cellular component organization | response to stimulus | response to stress | cellular nitrogen compound metabolic process | cellular biosynthetic process | DNA recombination | DNA repair | nitrogen compound metabolic process | double-strand break repair via homologous recombination | cellular response to DNA damage stimulus | cellular response to stress | biosynthetic process | DNA duplex unwinding | DNA strand elongation | DNA helicase activity | DNA metabolic process | metabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | cellular macromolecule biosynthetic process | recombinational repair | organelle organization | DNA strand elongation involved in DNA replication | DNA conformation change | heterocycle metabolic process | chromosome organization | cellular metabolic process | DNA replication | macromolecule metabolic process

GO Cellular Component

chromosome | intracellular membrane-bounded organelle | nuclear replication fork | cell | replication fork protection complex | nuclear lumen | replication fork | intracellular organelle | protein-containing complex | protein-DNA complex | nucleoplasm | nuclear chromosome | DNA replication preinitiation complex | membrane-bounded organelle | nucleus | GINS complex | organelle | membrane-enclosed lumen | intracellular