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QuickView for buthionine sulfoximine (compound)


PubChem
Name: Buthionine Sulfoximine
PubChem Compound ID: 21157
Description: A synthetic amino acid that depletes glutathione by irreversibly inhibiting gamma-glutamylcysteine synthetase. Inhibition of this enzyme is a critical step in glutathione biosynthesis. It has been shown to inhibit the proliferative response in human T-lymphocytes and inhibit macrophage activation. (J Biol Chem 1995;270(33):1945-7)
Molecular formula: C8H18N2O3S
Molecular weight: 222.306 g/mol
Synonyms:
2-Amino-4-(S-butylsulfonimidoyl)butanoic acid; 71765-30-5; DL-Buthionine-S,R-sulfoximine; L-Buthionine (SR)-sulfoximine; S-Butyl-DL-homocysteine-[S,R]-sulfoximine; Butanoic acid, 2-amino-4-(S-butylsulfonimidoyl)-; L-Buthionine-(S,R)-sulfoximine; EU-0100231; Buthionine sulphoximine; NCI60_002827.
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