Name: | Proto-Oncogene Proteins c-rel |
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Description: | Cellular DNA-binding proteins encoded by the rel gene (GENES, REL). They are expressed predominately in hematopoietic cells and may play a role in lymphocyte differentiation. Rel frequently combines with other related proteins (NF-KAPPA B, I-kappa B, relA) to form heterodimers that regulate transcription. Rearrangement or overexpression of c-rel can cause tumorigenesis. |
Synonyms: |
p68 c rel; c-rel, Proto-Oncogene Protein; Proteins, c-rel; Proto-Oncogene Protein c-rel; c-rel Proteins; rel Proto-Oncogene Product p68; Proto-Oncogene Proteins rel; Proto Oncogene Products c rel; c rel Proteins; c-rel, Proto-Oncogene Products.
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