Correlation Engine 2.0
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QuickView for cathepsin K (gene)

Gene Symbol:
CTSK Homo sapiens Homo sapiens
Full name:
cathepsin K
CTS02, CTSO, CTSO1, CTSO2, PKND, PYCD, cathepsin K, cathepsin O, cathepsin O1, cathepsin O2, cathepsin X
Genomic Location:
Chr 1: 149035311-149047436
The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to ...
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Bos taurus Danio rerio Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 1

Transcripts Names
Protein Names

GO Molecular Function

proteoglycan binding | protein-containing complex binding | hydrolase activity | carbohydrate derivative binding | cysteine-type peptidase activity | catalytic activity | serine hydrolase activity | collagen binding | cysteine-type endopeptidase activity | protein binding | serine-type endopeptidase activity | serine-type peptidase activity | endopeptidase activity | peptidase activity | fibronectin binding

GO Biological Process

extracellular structure organization | proteolysis | bone remodeling | tissue homeostasis | autophagy of mitochondrion | cellular process | organic substance catabolic process | proteolysis involved in cellular protein catabolic process | tissue remodeling | regulation of cell differentiation | anatomical structure homeostasis | regulation of cellular process | catabolic process | bone resorption | cellular component organization | collagen catabolic process | multicellular organismal homeostasis | regulation of epithelial cell differentiation | cellular protein catabolic process | extracellular matrix organization | mitochondrion organization | cysteine-type peptidase activity | nitrogen compound metabolic process | protein catabolic process | regulation of epidermis development | intramembranous ossification | regulation of keratinocyte differentiation | autophagy | homeostatic process | cysteine-type endopeptidase activity | organelle disassembly | protein metabolic process | cellular macromolecule catabolic process | metabolic process | organic substance metabolic process | serine-type endopeptidase activity | serine-type peptidase activity | organonitrogen compound catabolic process | endopeptidase activity | cellular protein metabolic process | collagen metabolic process | regulation of developmental process | organelle organization | ossification | cellular metabolic process | peptidase activity | extracellular matrix disassembly | regulation of epidermal cell differentiation | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

endolysosome | intracellular membrane-bounded organelle | cytoplasmic vesicle | cell | nuclear lumen | vacuolar lumen | cytoplasm | intracellular organelle | endomembrane system | nucleoplasm | vacuole | vesicle | endolysosome lumen | lytic vacuole | endosome | extracellular region | membrane-bounded organelle | endosome lumen | nucleus | organelle | lysosome | extracellular space | membrane-enclosed lumen | lysosomal lumen | intracellular vesicle | intracellular