QuickView for cd40 antigens (compound)

Name:	Antigens, CD40
Description:	A member of the tumor necrosis factor receptor superfamily with specificity for CD40 LIGAND. It is found on mature B-LYMPHOCYTES and some EPITHELIAL CELLS, lymphoid DENDRITIC CELLS. Evidence suggests that CD40-dependent activation of B-cells is important for generation of memory B-cells within the germinal centers. Mutations of the gene for CD40 antigen result in HYPER-IGM IMMUNODEFICIENCY SYNDROME, TYPE 3. Signaling of the receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
Synonyms:	Tumor Necrosis Factor Receptor Superfamily, Member 5; TNFRSF5 Receptor; Antigen, CD40; Receptor, TNFRSF5; Antigen, CDw40; CD40 Antigen; CDw40 Antigen; CD40 Antigens