QuickView for cdt1 (gene)

Gene Symbol:

CDT1 Homo sapiens

Full name:

chromatin licensing and DNA replication factor 1

Synonyms:

DUP, RIS2, DNA replication factor Cdt1, Double parked, Drosophila, homolog of

Genomic Location:

Chr 16: 87397687-87403167

Description:

The protein encoded by this gene is involved in the formation of the pre-replication complex that is necessary for DNA replication. The encoded protein can bind geminin, which prevents replication and may function to prevent this protein from initiating replication at inappropriate origins. Phosphorylation of this protein by cyclin A-dependent kina...

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The protein encoded by this gene is involved in the formation of the pre-replication complex that is necessary for DNA replication. The encoded protein can bind geminin, which prevents replication and may function to prevent this protein from initiating replication at inappropriate origins. Phosphorylation of this protein by cyclin A-dependent kinases results in degradation of the protein.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

E2F_Q6 ,  E2F_Q4 ,  E2F1DP1RB_01 ,  E2F1_Q6

Cytogenetic Map:

16q24.3

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