QuickView for cgrp (gene)

Gene Symbol:

Calca Mus musculus

Full name:

calcitonin/calcitonin-related polypeptide, alpha

Synonyms:

CA, CGRP-1, CGRP1, Calc, Calc1, Cgrp, Ct, Ctn, calcitonin gene-related peptide 1, alpha-type CGRP, calcitonin gene-related peptide I

Genomic Location:

Chr 7: 121775005-121779804

Description:

This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide (CGRP) and katacalcin. Alternative splicing of the mRNA results in multiple variants that encode either calcitonin or CGRP preproproteins. Post-translational processing of the calcitonin and CGRP propeptides results in either calcitonin and katacalcin, or CGRP, respe...

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This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide (CGRP) and katacalcin. Alternative splicing of the mRNA results in multiple variants that encode either calcitonin or CGRP preproproteins. Post-translational processing of the calcitonin and CGRP propeptides results in either calcitonin and katacalcin, or CGRP, respectively. Calcitonin and katacalcin modulate calcium levels in the blood stream. CGRP can function as a vasodilator and play a role in the transmission of pain. The human homolog of CGRP was found to have antimicrobial activity.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  Macaca mulatta ,  Canis lupus familiaris ,  Pan troglodytes ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TST1_01 ,  RORA1_01 ,  TATCTGG_MIR488 ,  CAGCTG_AP4_Q5 ,  TGAYRTCA_ATF3_Q6 ,  TGACCTY_ERR1_Q2 ,  TGTTTGY_HNF3_Q6 ,  TGCCAAR_NF1_Q6

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