QuickView for cyclin g2 (gene)

Gene Symbol:

CCNG2 Homo sapiens

Full name:

cyclin G2

Synonyms:

cyclin-G2

Genomic Location:

Chr 4: 78297551-78306970

Description:

The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The 8 species of cyclins reported in mammals, cyclins A through H, share a conserved amino acid sequence of about 90 residues called the cyclin box. The amino acid sequence of cyclin G is well conserved amon...

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The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The 8 species of cyclins reported in mammals, cyclins A through H, share a conserved amino acid sequence of about 90 residues called the cyclin box. The amino acid sequence of cyclin G is well conserved among mammals. The nucleotide sequence of cyclin G1 and cyclin G2 are 53% identical. Unlike cyclin G1, cyclin G2 contains a C-terminal PEST protein destabilization motif, suggesting that cyclin G2 expression is tightly regulated through the cell cycle.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  AAGCCAT_MIR135A_MIR135B ,  ATCMNTCCGY_UNKNOWN ,  ACTTTAT_MIR1425P ,  FAC1_01 ,  TTF1_Q6 ,  CYTAGCAAY_UNKNOWN ,  AAGCAAT_MIR137 ,  GGGAGGRR_MAZ_Q6 ,  ALPHACP1_01 ,  TGCGCANK_UNKNOWN ,  GCACTTT_MIR175P_MIR20A_MIR106A_MIR106B_MIR20B_MIR519D ,  GGGCGGR_SP1_Q6 ,  FOXO1_01 ,  CTTTAAR_UNKNOWN ,  GGCACTT_MIR519E ,  TAATTA_CHX10_01 ,  TTGTTT_FOXO4_01 ,  TGATTTRY_GFI1_01 ,  CTTTGT_LEF1_Q2

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-135 ,  Predicted Gene Targets for miR-142-5p ,  Predicted Gene Targets for miR-145 ,  Predicted Gene Targets for miR-20 ,  Predicted Gene Targets for miR-137

Cytogenetic Map:

4q21.1

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