Name: | Aldosterone Synthase |
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Description: | A mitochondrial cytochrome P450 enzyme that catalyzes the 18-hydroxylation of steroids in the presence of molecular oxygen and NADPH-specific flavoprotein. This enzyme, encoded by CYP11B2 gene, is important in the conversion of CORTICOSTERONE to 18-hydroxycorticosterone and the subsequent conversion to ALDOSTERONE. |
Synonyms: |
Aldosterone Synthase Cytochrome P-450; CYP 11B2; Cytochrome P450 11B2; Cytochrome P-450c11AS; Cytochrome P-450 CYP11B2; Steroid 18 Hydroxylase; P450c11AS; Cytochrome P 450c11AS; Cytochrome P 450 CYP11B2; CYP11B2.
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