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QuickView for cytoglobin (gene)


Gene Symbol:
CYGB Homo sapiens Homo sapiens
Full name:
cytoglobin
Synonyms:
HGB, STAP, cytoglobin, histoglobin, stellate cell activation-associated protein
Genomic Location:
Chr 17: 72035035-72045377
Description:
This gene encodes a globin protein found in vertebrate cells. The encoded protein is described as a hexacoordinate hemoglobin which binds ligand differently from the pentacoordinate hemoglobins involved in oxygen transport, and may be involved in protection during oxidative stress. This gene is located on chromosome 17 in the same region as a retin...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Bos taurus Danio rerio Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 17
17q25.1





GO Molecular Function

cofactor binding | fatty acid peroxidase activity | peroxidase activity | cation binding | antioxidant activity | iron ion binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | nitric oxide dioxygenase activity | ion binding | organic cyclic compound binding | oxygen carrier activity | tetrapyrrole binding | oxygen binding | protein binding | catalase activity | dioxygenase activity | transition metal ion binding | heme binding | drug binding | oxidoreductase activity, acting on peroxide as acceptor | metal ion binding | heterocyclic compound binding | oxidoreductase activity | small molecule binding

GO Biological Process

regulation of localization | negative regulation of collagen biosynthetic process | establishment of localization | fatty acid peroxidase activity | negative regulation of cellular process | peroxidase activity | response to drug | regulation of fibroblast migration | cellular process | regulation of cell motility | localization | cellular detoxification | antioxidant activity | response to hypoxia | negative regulation of cell migration | negative regulation of cell motility | regulation of cellular process | regulation of metabolic process | cellular lipid metabolic process | response to stimulus | monocarboxylic acid metabolic process | response to stress | cellular response to toxic substance | negative regulation of metabolic process | response to oxygen levels | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | regulation of collagen biosynthetic process | regulation of catalytic activity | lipid metabolic process | regulation of nitric-oxide synthase activity | regulation of hepatic stellate cell activation | regulation of cell migration | small molecule metabolic process | regulation of cellular component movement | response to oxidative stress | negative regulation of fibroblast migration | nitric oxide dioxygenase activity | response to toxic substance | oxygen transport | negative regulation of cell activation | regulation of collagen metabolic process | oxygen carrier activity | lipid modification | regulation of locomotion | carboxylic acid metabolic process | catalase activity | metabolic process | cellular oxidant detoxification | oxidation-reduction process | organic substance metabolic process | negative regulation of biosynthetic process | regulation of cell activation | negative regulation of cellular component movement | dioxygenase activity | fatty acid metabolic process | lipid oxidation | drug transport | regulation of oxidoreductase activity | organic acid metabolic process | detoxification | fatty acid oxidation | negative regulation of hepatic stellate cell activation | oxidoreductase activity, acting on peroxide as acceptor | cellular metabolic process | oxidoreductase activity | negative regulation of locomotion

GO Cellular Component

intracellular membrane-bounded organelle | neuron projection | somatodendritic compartment | cell body | cell | nuclear lumen | neuronal cell body | cytoplasm | intracellular organelle | nuclear body | cell projection | nucleoplasm | nuclear speck | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular