QuickView for cytoglobin (gene)

Gene Symbol:

CYGB Homo sapiens

Full name:

cytoglobin

Synonyms:

HGB, STAP, cytoglobin, histoglobin, stellate cell activation-associated protein

Genomic Location:

Chr 17: 72035035-72045377

Description:

This gene encodes a globin protein found in vertebrate cells. The encoded protein is described as a hexacoordinate hemoglobin which binds ligand differently from the pentacoordinate hemoglobins involved in oxygen transport, and may be involved in protection during oxidative stress. This gene is located on chromosome 17 in the same region as a retin...

View Full Description

This gene encodes a globin protein found in vertebrate cells. The encoded protein is described as a hexacoordinate hemoglobin which binds ligand differently from the pentacoordinate hemoglobins involved in oxygen transport, and may be involved in protection during oxidative stress. This gene is located on chromosome 17 in the same region as a retinal gene which is mutated in progressive rod-cone degeneration, but in the opposite orientation.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Bos taurus ,  Danio rerio ,  Canis lupus familiaris ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AML_Q6 ,  WGTTNNNNNAAA_UNKNOWN ,  TAGCTTT_MIR9 ,  CTTTGA_LEF1_Q2 ,  TFIII_Q6 ,  GGGCGGR_SP1_Q6 ,  GTGCCAA_MIR96 ,  COREBINDINGFACTOR_Q6 ,  AGGAAGC_MIR5163P

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-96 ,  Predicted Gene Targets for miR-409-5p

Cytogenetic Map:

17q25.1

search → result