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QuickView for dalfopristin (compound)
PubChem
| Name: | dalfopristin |
|---|---|
| PubChem Compound ID: | 5366 |
| Molecular formula: | C34H50N4O9S |
| Molecular weight: | 690.848 g/mol |
DrugBank
Identification
| Name: | dalfopristin |
|---|---|
| Name (isomeric): | DB01764 |
| Drug Type: | small molecule |
| Synonyms: |
Dalfopristine [inn-french]; Dalfopristina [inn-spanish]; Dalfopristinum [inn-latin]
|
| Brand name mixture: | Synercid(Dalfopristin + Quinupristin) |
| Category: | Anti-Bacterial Agents, Antibacterial Agents |
| CAS number: | 112362-50-2 |
Pharmacology
| Indication: | For the treatment of bacterial infections (usually in combination with quinupristin). |
|---|---|
| Pharmacology: | Dalfopristin is a streptogramin antibiotic, derived from pristinamycin IIA. |
| Mechanism of Action: | The site of action of dalfopristin is the bacterial ribosome. Dalfopristin has been shown to inhibit the early phase of protein synthesis. |
| Protein binding: | Moderate |
| Biotransformation: | Converted to an active non-conjugated metabolite by hydrolysis. |
| Half Life: | The elimination half-life is approximately 0.70 hours. |
| Affected organisms: | Enteric bacteria and other eubacteria |
Targets
