QuickView for eco (gene)
- Gene Symbol:
- ICK
Homo sapiens - Full name:
- intestinal cell kinase
- Synonyms:
- ECO, LCK2, MRK, serine/threonine-protein kinase ICK, MAK-related kinase, hICK, intestinal cell (MAK-like) kinase, laryngeal cancer kinase 2, serine/threonine protein kinase
- Genomic Location:
- Chr 6: 52974057-53034559
- Description:
-
Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein ...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for miR-101 , Predicted Gene Targets for miR-144 , Predicted Gene Targets for miR-183 , Predicted Gene Targets for miR-200b , Predicted Gene Targets for miR-218 , Predicted Gene Targets for miR-26 , Predicted Gene Targets for miR-30 , Predicted Gene Targets for miR-369-3p , Predicted Gene Targets for miR-381 , Predicted Gene Targets for miR-382
- Cytogenetic Map:
-
6p12.1
GO Molecular Function
cation binding | magnesium ion binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | metal ion binding | heterocyclic compound binding | small molecule binding
GO Biological Process
microtubule-based transport | intracellular signal transduction | establishment of localization | intracellular transport | microtubule-based process | cellular process | localization | establishment of localization in cell | cytoskeleton-dependent intracellular transport | regulation of cellular process | regulation of metabolic process | cellular component organization | response to stimulus | protein serine/threonine kinase activity | microtubule-based movement | cellular localization | cellular component assembly | protein modification process | macromolecule modification | organelle assembly | nitrogen compound metabolic process | multicellular organism development | phosphorus metabolic process | regulation of gene expression | cell projection assembly | phosphorylation | protein phosphorylation | phosphate-containing compound metabolic process | cell communication | intraciliary transport | protein-containing complex localization | intraciliary retrograde transport | protein metabolic process | anatomical structure development | cell projection organization | metabolic process | transport along microtubule | protein kinase activity | organic substance metabolic process | cilium assembly | cilium organization | signaling | cellular protein metabolic process | kinase activity | developmental process | organelle organization | cellular protein modification process | intraciliary anterograde transport | cellular metabolic process | signal transduction | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | microtubule organizing center | fibrillar center | cell | nuclear lumen | nucleolus | cytoplasm | intracellular organelle | cell projection | cilium | microtubule cytoskeleton | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | ciliary base | cytosol | cytoskeleton | ciliary tip | intracellular | ciliary basal body
