QuickView for ephrin B1 (gene)
- Gene Symbol:
- EFNB1
Homo sapiens - Full name:
- ephrin B1
- Synonyms:
- CFND, CFNS, EFB1, EFL3, EPLG2, Elk-L, LERK2, ephrin-B1, ELK ligand, eph-related receptor tyrosine kinase ligand 2
- Genomic Location:
- Chr X: 67965556-67978728
- Description:
-
The protein encoded by this gene is a type I membrane protein and a ligand of Eph-related receptor tyrosine kinases. It may play a role in cell adhesion and function in the development or maintenance of the nervous system.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Bos taurus , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for miR-103 , Predicted Gene Targets for miR-15 , Predicted Gene Targets for miR-150 , Predicted Gene Targets for miR-185 , Predicted Gene Targets for miR-20 , Predicted Gene Targets for miR-208 , Predicted Gene Targets for miR-34 , Predicted Gene Targets for miR-381 , Predicted Gene Targets for miR-503 , Predicted Gene Targets for miR-124a
- Cytogenetic Map:
-
Xq13.1
GO Molecular Function
ephrin receptor binding | signaling receptor binding | catalytic activity | protein tyrosine kinase activity | protein binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | kinase activity
GO Biological Process
cell morphogenesis | cell motility | neuron projection morphogenesis | peptidyl-amino acid modification | regulation of immune system process | positive regulation of lymphocyte activation | cell differentiation | nervous system development | lymphocyte costimulation | cell part morphogenesis | neurogenesis | positive regulation of cell adhesion | peptidyl-tyrosine phosphorylation | generation of neurons | mesenchyme development | pattern specification process | cellular process | localization | cell projection morphogenesis | neuron development | axon guidance | tissue development | regulation of cellular process | ephrin receptor signaling pathway | cellular component organization | response to stimulus | cell morphogenesis involved in neuron differentiation | mesenchymal cell development | positive regulation of immune system process | neuron projection guidance | positive regulation of lymphocyte proliferation | regulation of cell proliferation | positive regulation of cell-cell adhesion | positive regulation of cell activation | positive regulation of T cell activation | protein modification process | regulation of cell adhesion | embryo development | macromolecule modification | cell-cell signaling | locomotion | positive regulation of mononuclear cell proliferation | system development | nitrogen compound metabolic process | multicellular organism development | cell migration | phosphorus metabolic process | regulation of T cell activation | axon development | regulation of lymphocyte activation | enzyme linked receptor protein signaling pathway | axonogenesis | stem cell differentiation | positive regulation of T cell proliferation | phosphorylation | protein phosphorylation | cell morphogenesis involved in differentiation | phosphate-containing compound metabolic process | neural crest cell migration | cell communication | positive regulation of cell proliferation | protein tyrosine kinase activity | neuron differentiation | protein metabolic process | anatomical structure development | cell surface receptor signaling pathway | cell projection organization | metabolic process | mesenchymal cell differentiation | positive regulation of leukocyte activation | cell adhesion | protein kinase activity | neuron projection development | organic substance metabolic process | animal organ development | regulation of cell activation | stem cell development | T cell costimulation | signaling | cell development | regulation of T cell proliferation | cellular protein metabolic process | anatomical structure morphogenesis | kinase activity | developmental process | cellular protein modification process | regulation of cell-cell adhesion | neural crest cell differentiation | transmembrane receptor protein tyrosine kinase signaling pathway | immune system process | cellular metabolic process | ameboidal-type cell migration | chemotaxis | neural crest cell development | positive regulation of leukocyte cell-cell adhesion | signal transduction | embryonic pattern specification | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | synapse | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | membrane microdomain | plasma membrane | membrane raft | vesicle | extracellular exosome | integral component of plasma membrane | extracellular region | membrane-bounded organelle | extracellular vesicle | nucleus | organelle | extracellular space | cell periphery | intracellular | membrane | intrinsic component of plasma membrane
