QuickView for exportin 6 (gene)

Gene Symbol:

XPO6 Homo sapiens

Full name:

exportin 6

Synonyms:

EXP6, RANBP20, exportin-6, ran-binding protein 20

Genomic Location:

Chr 16: 28016817-28130691

Description:

The protein encoded by this gene is a member of the importin-beta family. Members of this family are regulated by the GTPase Ran to mediate transport of cargo across the nuclear envelope. This protein has been shown to mediate nuclear export of profilin-actin complexes. A pseudogene of this gene is located on the long arm of chromosome 14. Alternat...

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The protein encoded by this gene is a member of the importin-beta family. Members of this family are regulated by the GTPase Ran to mediate transport of cargo across the nuclear envelope. This protein has been shown to mediate nuclear export of profilin-actin complexes. A pseudogene of this gene is located on the long arm of chromosome 14. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATA1_03 ,  GATA3_01 ,  GATA_Q6 ,  GATAAGR_GATA_C ,  LMO2COM_02 ,  AP1_Q2_01 ,  GATA6_01 ,  GATA1_02 ,  AHRARNT_01 ,  ER_Q6_02 ,  NFKB_Q6_01 ,  NFKB_Q6 ,  NFKB_C ,  SF1_Q6

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-1 ,  Predicted Gene Targets for miR-539

miRNA binding sites
(Source: miRecords):

hsa-miR-1 Targeted Genes

Cytogenetic Map:

16p12.1

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