QuickView for frizzled 4 (gene)

Gene Symbol:

FZD4 Homo sapiens

Full name:

frizzled class receptor 4

Synonyms:

CD344, EVR1, FEVR, FZD4S, Fz-4, Fz4, FzE4, GPCR, hFz4, frizzled-4, WNT receptor frizzled-4, frizzled 4, seven transmembrane spanning receptor, frizzled family receptor 4, frizzled homolog 4

Genomic Location:

Chr 11: 86334369-86344081

Description:

This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of...

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This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Bos taurus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

OCT1_07 ,  OCT1_05 ,  GATA1_03 ,  OCT1_01 ,  GATA3_01 ,  YATGNWAAT_OCT_C ,  OCT_Q6 ,  CTTTGCA_MIR527 ,  TGTGTGA_MIR377 ,  GTACTGT_MIR101 ,  ATGTACA_MIR493 ,  GATAAGR_GATA_C ,  OCT1_Q5_01 ,  OCT_C ,  GATA1_04 ,  OCT1_Q6 ,  TTGGGAG_MIR150 ,  GGATTA_PITX2_Q2 ,  CAGGTG_E12_Q6 ,  CTACCTC_LET7A_LET7B_LET7C_LET7D_LET7E_LET7F_MIR98_LET7G_LET7I ,  GGGCGGR_SP1_Q6 ,  ATGTTAA_MIR302C ,  GACAATC_MIR219 ,  PITX2_Q2 ,  LMO2COM_02 ,  ACTGCAG_MIR173P ,  TGCCAAR_NF1_Q6 ,  YCATTAA_UNKNOWN ,  GTGCCTT_MIR506 ,  GTGTCAA_MIR514 ,  CTGCAGY_UNKNOWN ,  ER_Q6_02 ,  CACBINDINGPROTEIN_Q6 ,  GGCAGTG_MIR3243P ,  CRX_Q4 ,  CEBPGAMMA_Q6 ,  GGGTGGRR_PAX4_03 ,  ACACTGG_MIR199A_MIR199B ,  AAGCACA_MIR218

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for let-7 ,  Predicted Gene Targets for miR-101 ,  Predicted Gene Targets for miR-144 ,  Predicted Gene Targets for miR-150 ,  Predicted Gene Targets for miR-199 ,  Predicted Gene Targets for miR-20 ,  Predicted Gene Targets for miR-208 ,  Predicted Gene Targets for miR-218 ,  Predicted Gene Targets for miR-219 ,  Predicted Gene Targets for miR-27 ,  Predicted Gene Targets for miR-28 ,  Predicted Gene Targets for miR-324-3p ,  Predicted Gene Targets for miR-377 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-493-5p ,  Predicted Gene Targets for miR-499 ,  Predicted Gene Targets for miR-543

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Cytogenetic Map:

11q14.2

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