QuickView for glutamate receptor ionotropic, ampa 4 (gene)

Gene Symbol:

Gria4 Mus musculus

Full name:

glutamate receptor, ionotropic, AMPA4 (alpha 4)

Synonyms:

GluA4, GluR-D, Glur-4, Glur4, Gluralpha4, spkw1, glutamate receptor 4, AMPA-selective glutamate receptor 4, glutamate receptor channel alpha 4, glutamate receptor ionotropic, AMPA 4, spike wave 1

Genomic Location:

Chr 9: 4417896-4796142

Description:

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on t...

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Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

E2F_01 ,  E2F_02 ,  E2F_Q4 ,  E2F_Q6 ,  E2F1_Q3 ,  E2F1_Q6 ,  CTGCAGY_UNKNOWN ,  E2F_03 ,  HSF_Q6 ,  E2F1DP1_01 ,  E2F1DP2_01 ,  E2F4DP1_01 ,  E2F4DP2_01 ,  E2F1DP1RB_01 ,  E2F_Q6_01 ,  ER_Q6_02 ,  TGACATY_UNKNOWN ,  TGAYRTCA_ATF3_Q6 ,  TGACCTY_ERR1_Q2

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