QuickView for glutathione reductase (gene)
- Gene Symbol:
- Gsr
Rattus norvegicus - Full name:
- glutathione-disulfide reductase
- Synonyms:
- glutathione reductase, GR, GRase, glutathione reductase, mitochondrial
- Genomic Location:
- Chr 16: 62255562-62298458
- Description:
-
catalyzes the conversion of glutathione and NADP+ to glutathione disulfide and NADPH + H+; may play a role in spermatogenesis
- Orthologs:
- Homo sapiens , Mus musculus , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio , Gallus gallus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
oxidoreductase activity, acting on NAD(P)H | NADP binding | cofactor binding | peptide binding | modified amino acid binding | glutathione-disulfide reductase activity | antioxidant activity | nucleotide binding | flavin adenine dinucleotide binding | coenzyme binding | catalytic activity | anion binding | oxidoreductase activity, acting on a sulfur group of donors | glutathione disulfide oxidoreductase activity | amide binding | identical protein binding | ion binding | organic cyclic compound binding | disulfide oxidoreductase activity | protein binding | protein homodimerization activity | protein dimerization activity | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor | glutathione binding | peptide disulfide oxidoreductase activity | selenodiglutathione-disulfide reductase activity | heterocyclic compound binding | oxidoreductase activity | small molecule binding
GO Biological Process
response to extracellular stimulus | oxidoreductase activity, acting on NAD(P)H | response to nutrient levels | sulfur compound metabolic process | glutathione metabolic process | response to metal ion | male gamete generation | response to drug | response to antibiotic | cellular process | glutathione-disulfide reductase activity | cellular homeostasis | cellular detoxification | antioxidant activity | multicellular organismal reproductive process | response to inorganic substance | gamete generation | regulation of cellular process | response to stimulus | response to stress | cell redox homeostasis | reproduction | response to alcohol | cellular nitrogen compound metabolic process | cellular response to toxic substance | response to ischemia | cofactor metabolic process | response to iron ion | response to ethanol | response to nicotine | nitrogen compound metabolic process | reproductive process | response to activity | cellular response to oxidative stress | oxidoreductase activity, acting on a sulfur group of donors | cellular response to stress | response to lipid | glutathione disulfide oxidoreductase activity | cellular amide metabolic process | response to nutrient | response to oxidative stress | response to cadmium ion | response to vitamin A | response to toxic substance | homeostatic process | peptide metabolic process | disulfide oxidoreductase activity | multicellular organism reproduction | response to organic substance | response to mechanical stimulus | metabolic process | cellular oxidant detoxification | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor | oxidation-reduction process | organic substance metabolic process | response to vitamin | response to iron(III) ion | peptide disulfide oxidoreductase activity | developmental process | spermatogenesis | selenodiglutathione-disulfide reductase activity | detoxification | cellular modified amino acid metabolic process | cellular metabolic process | oxidoreductase activity | aging | sexual reproduction | response to auditory stimulus | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | cell | external side of plasma membrane | cytoplasm | intracellular organelle | plasma membrane | mitochondrion | membrane-bounded organelle | organelle | cell periphery | cytosol | cell surface | intracellular | membrane
