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QuickView for glypican 1 (gene)


Gene Symbol:
GPC1 Homo sapiens Homo sapiens
Full name:
glypican 1
Synonyms:
glypican, glypican-1, glypican proteoglycan 1
Genomic Location:
Chr 2: 241023788-241056168
Description:
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These prot...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Canis lupus familiaris Bos taurus Danio rerio Pan troglodytes
External Links:
Entrez Gene
Cytogenetic Map:
chr 2
2q37.3


Transcripts Names
NM_002081
XM_011510976
Protein Names
P35052
Q53QM4
H7C410



GO Molecular Function

cation binding | growth factor binding | fibroblast growth factor binding | extracellular matrix binding | ion binding | copper ion binding | laminin binding | protein binding | transition metal ion binding | metal ion binding

GO Biological Process

cell morphogenesis | cell motility | neuron projection morphogenesis | positive regulation of skeletal muscle tissue development | positive regulation of striated muscle tissue development | Schwann cell differentiation | negative regulation of cellular process | positive regulation of developmental process | cell differentiation | nervous system development | cell part morphogenesis | neurogenesis | generation of neurons | regulation of skeletal muscle cell differentiation | cellular process | positive regulation of skeletal muscle cell differentiation | peripheral nervous system development | organic substance catabolic process | localization | axon ensheathment | cell projection morphogenesis | negative regulation of signaling | neuron development | carbohydrate derivative catabolic process | regulation of striated muscle tissue development | axon guidance | glycosaminoglycan catabolic process | regulation of cell differentiation | regulation of cellular process | proteoglycan catabolic process | gliogenesis | catabolic process | negative regulation of fibroblast growth factor receptor signaling pathway | cellular component organization | cellular lipid metabolic process | glycosaminoglycan biosynthetic process | response to stimulus | cell morphogenesis involved in neuron differentiation | neuron projection guidance | ensheathment of neurons | proteoglycan metabolic process | carbohydrate derivative biosynthetic process | cellular component assembly | leukocyte migration | locomotion | retinoid metabolic process | regulation of skeletal muscle tissue development | system development | nitrogen compound metabolic process | regulation of signal transduction | myelination | multicellular organism development | cell migration | positive regulation of muscle organ development | lipid metabolic process | axon development | protein catabolic process | regulation of fibroblast growth factor receptor signaling pathway | negative regulation of cellular response to growth factor stimulus | heparan sulfate proteoglycan catabolic process | heparan sulfate proteoglycan metabolic process | axonogenesis | positive regulation of cell differentiation | biosynthetic process | glial cell differentiation | cell morphogenesis involved in differentiation | regulation of cellular response to growth factor stimulus | neuron differentiation | protein metabolic process | cellular macromolecule catabolic process | anatomical structure development | cell projection organization | metabolic process | neuron projection development | organic substance metabolic process | diterpenoid metabolic process | positive regulation of muscle tissue development | anatomical structure formation involved in morphogenesis | organonitrogen compound catabolic process | regulation of cell communication | negative regulation of signal transduction | cell development | anatomical structure morphogenesis | isoprenoid metabolic process | regulation of developmental process | developmental process | myelin assembly | carbohydrate derivative metabolic process | immune system process | cellular metabolic process | glycoprotein catabolic process | glycoprotein metabolic process | chemotaxis | regulation of signaling | glycosaminoglycan metabolic process | regulation of muscle organ development | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | extracellular matrix | cytoplasmic vesicle | cell | nuclear lumen | vacuolar lumen | intrinsic component of membrane | cytoplasm | collagen-containing extracellular matrix | intracellular organelle | membrane microdomain | anchored component of plasma membrane | Golgi apparatus | endomembrane system | nucleoplasm | plasma membrane | membrane raft | vacuole | vesicle | extracellular exosome | anchored component of membrane | lytic vacuole | endosome | extracellular region | membrane-bounded organelle | extracellular vesicle | nucleus | organelle | lysosome | extracellular space | cell periphery | membrane-enclosed lumen | lysosomal lumen | cytosol | intracellular vesicle | intracellular | membrane | intrinsic component of plasma membrane | Golgi lumen