Name: | GRB2 Adaptor Protein |
---|---|
Description: | A signal transducing adaptor protein that links extracellular signals to the MAP KINASE SIGNALING SYSTEM. Grb2 associates with activated EPIDERMAL GROWTH FACTOR RECEPTOR and PLATELET-DERIVED GROWTH FACTOR RECEPTORS via its SH2 DOMAIN. It also binds to and translocates the SON OF SEVENLESS PROTEINS through its SH3 DOMAINS to activate PROTO-ONCOGENE PROTEIN P21(RAS). |
Synonyms: |
Growth Factor Receptor-Bound Protein-2; Abundant Src Homology Protein; Growth Factor Receptor Bound Protein 2
|