QuickView for hPL (gene)

Gene Symbol:

LGALS1 Homo sapiens

Full name:

galectin 1

Synonyms:

GAL1, GBP, galectin-1, 14 kDa laminin-binding protein, 14 kDa lectin, HBL, HLBP14, HPL, S-Lac lectin 1, beta-galactoside-binding lectin L-14-I, beta-galactoside-binding protein 14kDa, gal-1, galaptin, lactose-binding lectin 1, lectin, galactoside-binding, soluble, 1, putative MAPK-activating protein PM12

Genomic Location:

Chr 22: 36401559-36405755

Description:

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This gene product may act as an autocrine negative growth factor that regulates cell proliferation.

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This gene product may act as an autocrine negative growth factor that regulates cell proliferation.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Danio rerio ,  Canis lupus familiaris ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  MAZR_01 ,  TGANTCA_AP1_C ,  NFAT_Q6 ,  GCANCTGNY_MYOD_Q6 ,  E2F1_Q4 ,  GGGAGGRR_MAZ_Q6 ,  GGGYGTGNY_UNKNOWN ,  GGGCGGR_SP1_Q6 ,  E2F1_Q3_01 ,  E47_01 ,  E2F_03 ,  GGCAGCT_MIR22 ,  AP4_Q6_01 ,  CTGCAGY_UNKNOWN ,  CAGCTG_AP4_Q5

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-22

Cytogenetic Map:

22q13.1

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