Name: | haloprogin |
---|---|
PubChem Compound ID: | 3561 |
Molecular formula: | C9H4Cl3IO |
Molecular weight: | 361.39 g/mol |
Synonyms: |
AIDS097759; 777-11-7; Halotex (TN); Haloprogina [INN-Spanish]; Haloprogin (JAN/USAN); 2,4,5-Trichlorophenyl gamma-iodopropargil ether; Haloprogin [USAN:INN:JAN]; 2,4,5-Trichlorophenyl .gamma.-iodopropargyl ether; Ether, 3-iodo-2-propynyl 2,4,5-trichlorophenyl; 1,2,4-trichloro-5-[(3-iodo-2-propynyl) oxy]benzene.
show more » |
Name: | haloprogin |
---|---|
Name (isomeric): | DB00793 |
Drug Type: | small molecule |
Brand: | Mycanden, Haloproginum [INN-Latin], Haloprogina [INN-Spanish], Halotex, Mycilan, Aloprogen, Polik, Haloprogine [INN-French], Haloprogin [USAN:INN:JAN] |
Category: | Anti-fungal Agents |
CAS number: | 777-11-7 |
Indication: | Used to treat fungal (Tinea) skin infections such as athlete's foot, jock itch, ringworm, and tinea versicolor. |
---|---|
Pharmacology: |
Used as a topical ointment or cream in the treatment of Tinea infections. Tinea infections are superficial fungal infections caused by three species of fungi collectively known as dermatophytes (Trichophyton, Microsporum and Epidermophyton). Commonly these infections are named for the body part affected, including tinea corporis (general skin), tin...
show more » |
Mechanism of Action: |
Haloprogin is a halogenated phenolic ether administered topically for dermotaphytic infections. The mechanism of action is unknown, but is thought to be via inhibition of oxygen uptake and disruption of yeast membrane structure and function. There is a higher incidence of cutaneous side effects with haloprogin, including irritation, burning, vesicu...
show more » |
Affected organisms: | Dermatophytic fungi including Trichophyton, Microsporum and Epidermophyton |