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QuickView for haloprogin (compound)


PubChem
Name: haloprogin
PubChem Compound ID: 3561
Molecular formula: C9H4Cl3IO
Molecular weight: 361.39 g/mol
Synonyms:
AIDS097759; 777-11-7; Halotex (TN); Haloprogina [INN-Spanish]; Haloprogin (JAN/USAN); 2,4,5-Trichlorophenyl gamma-iodopropargil ether; Haloprogin [USAN:INN:JAN]; 2,4,5-Trichlorophenyl .gamma.-iodopropargyl ether; Ether, 3-iodo-2-propynyl 2,4,5-trichlorophenyl; 1,2,4-trichloro-5-[(3-iodo-2-propynyl) oxy]benzene.
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DrugBank
Identification
Name: haloprogin
Name (isomeric): DB00793
Drug Type: small molecule
Brand: Mycanden, Haloproginum [INN-Latin], Haloprogina [INN-Spanish], Halotex, Mycilan, Aloprogen, Polik, Haloprogine [INN-French], Haloprogin [USAN:INN:JAN]
Category: Anti-fungal Agents
CAS number: 777-11-7
Pharmacology
Indication: Used to treat fungal (Tinea) skin infections such as athlete's foot, jock itch, ringworm, and tinea versicolor.
Pharmacology:
Used as a topical ointment or cream in the treatment of Tinea infections. Tinea infections are superficial fungal infections caused by three species of fungi collectively known as dermatophytes (Trichophyton, Microsporum and Epidermophyton). Commonly these infections are named for the body part affected, including tinea corporis (general skin), tin...
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Mechanism of Action:
Haloprogin is a halogenated phenolic ether administered topically for dermotaphytic infections. The mechanism of action is unknown, but is thought to be via inhibition of oxygen uptake and disruption of yeast membrane structure and function. There is a higher incidence of cutaneous side effects with haloprogin, including irritation, burning, vesicu...
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Affected organisms: Dermatophytic fungi including Trichophyton, Microsporum and Epidermophyton