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QuickView for hematopoietic growth factor (gene)


Gene Symbol:
IL3 Homo sapiens Homo sapiens
Full name:
interleukin 3
Synonyms:
IL-3, MCGF, MULTI-CSF, interleukin-3, P-cell stimulating factor, colony-stimulating factor, multiple, hematopoietic growth factor, mast-cell growth factor, multilineage-colony-stimulating factor, multipotential colony-stimulating factor
Genomic Location:
Chr 5: 131424246-131426795
Description:
The protein encoded by this gene is a potent growth promoting cytokine. This cytokine is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it m...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 5
5q31.1


Transcripts Names
NM_000588
Protein Names
Q6GS87
P08700



GO Molecular Function

guanyl-nucleotide exchange factor activity | GTPase binding | interleukin-3 receptor binding | enzyme binding | signaling receptor binding | cytokine receptor binding | Ras GTPase binding | molecular function regulator | catalytic activity | protein tyrosine kinase activity | protein binding | receptor regulator activity | growth factor activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | Ras guanyl-nucleotide exchange factor activity | receptor ligand activity | protein kinase activity | transferase activity | small GTPase binding | growth factor receptor binding | kinase activity

GO Biological Process

guanyl-nucleotide exchange factor activity | response to cytokine | intracellular signal transduction | positive regulation of peptidyl-tyrosine phosphorylation | peptidyl-amino acid modification | nervous system development | positive regulation of phosphate metabolic process | peptidyl-tyrosine phosphorylation | cellular process | immune system development | regulation of response to cytokine stimulus | regulation of tyrosine phosphorylation of STAT protein | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of metabolic process | positive regulation of cellular protein metabolic process | MAPK cascade | response to stimulus | regulation of peptidyl-tyrosine phosphorylation | positive regulation of protein metabolic process | signal transduction by protein phosphorylation | positive regulation of JAK-STAT cascade | regulation of cell proliferation | hemopoiesis | protein modification process | embryo development | macromolecule modification | cell-cell signaling | molecular function regulator | system development | nitrogen compound metabolic process | regulation of signal transduction | multicellular organism development | phosphorus metabolic process | embryonic hemopoiesis | regulation of phosphorylation | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of nitrogen compound metabolic process | positive regulation of STAT cascade | cytokine-mediated signaling pathway | positive regulation of intracellular signal transduction | cellular response to cytokine stimulus | regulation of cellular protein metabolic process | phosphorylation | protein phosphorylation | phosphate-containing compound metabolic process | cell communication | regulation of cellular metabolic process | positive regulation of tyrosine phosphorylation of STAT protein | regulation of protein metabolic process | positive regulation of signal transduction | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of cytokine-mediated signaling pathway | protein tyrosine kinase activity | regulation of signaling receptor activity | receptor regulator activity | protein metabolic process | positive regulation of protein modification process | response to organic substance | regulation of JAK-STAT cascade | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | growth factor activity | metabolic process | embryonic organ development | Ras guanyl-nucleotide exchange factor activity | receptor ligand activity | immune response | protein kinase activity | organic substance metabolic process | animal organ development | regulation of phosphate metabolic process | regulation of cell communication | signaling | positive regulation of phosphorylation | cellular protein metabolic process | kinase activity | developmental process | cellular protein modification process | positive regulation of metabolic process | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | cellular response to organic substance | positive regulation of signaling | signal transduction | regulation of signaling | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

cell | extracellular region | extracellular space | intracellular