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QuickView for hemopexin (gene)


Gene Symbol:
HPX Homo sapiens Homo sapiens
Full name:
hemopexin
Synonyms:
HX, hemopexin, beta-1B-glycoprotein
Genomic Location:
Chr 11: 6409017-6418769
Description:
This gene encodes a plasma glycoprotein that binds heme with high affinity. The encoded protein is an acute phase protein that transports heme from the plasma to the liver and may be involved in protecting cells from oxidative stress.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Bos taurus Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 11
11p15.4


Transcripts Names
NM_000613
Protein Names
P02790
Q9BS19
B2R957



GO Molecular Function

metallopeptidase activity | cation binding | transmembrane transporter activity | hydrolase activity | catalytic activity | transporter activity | ion binding | protein binding | heme transporter activity | metal ion binding | peptidase activity

GO Biological Process

positive regulation of immune response | metallopeptidase activity | proteolysis | positive regulation of peptidyl-tyrosine phosphorylation | establishment of localization | regulation of immune system process | cellular chemical homeostasis | positive regulation of phosphate metabolic process | regulation of response to interferon-gamma | cellular process | localization | cellular homeostasis | positive regulation of humoral immune response mediated by circulating immunoglobulin | positive regulation of immune effector process | positive regulation of adaptive immune response | regulation of response to cytokine stimulus | regulation of tyrosine phosphorylation of STAT protein | positive regulation of nitrogen compound metabolic process | interspecies interaction between organisms | heme metabolic process | porphyrin-containing compound metabolic process | regulation of immune response | regulation of cellular process | regulation of metabolic process | transmembrane transporter activity | regulation of interferon-gamma-mediated signaling pathway | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | cellular aromatic compound metabolic process | positive regulation of innate immune response | regulation of peptidyl-tyrosine phosphorylation | positive regulation of immune system process | positive regulation of protein metabolic process | positive regulation of immunoglobulin production | positive regulation of JAK-STAT cascade | regulation of humoral immune response mediated by circulating immunoglobulin | regulation of humoral immune response | cofactor metabolic process | metal ion homeostasis | positive regulation of interferon-gamma-mediated signaling pathway | positive regulation of response to cytokine stimulus | nitrogen compound metabolic process | regulation of signal transduction | regulation of phosphorylation | organic substance transport | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular ion homeostasis | regulation of nitrogen compound metabolic process | positive regulation of STAT cascade | positive regulation of intracellular signal transduction | vesicle-mediated transport | positive regulation of humoral immune response | regulation of cellular protein metabolic process | positive regulation of immunoglobulin mediated immune response | cation homeostasis | cellular cation homeostasis | regulation of cellular metabolic process | positive regulation of tyrosine phosphorylation of STAT protein | regulation of protein metabolic process | positive regulation of signal transduction | homeostatic process | regulation of protein phosphorylation | regulation of cytokine-mediated signaling pathway | iron ion homeostasis | viral process | protein metabolic process | positive regulation of protein modification process | regulation of innate immune response | regulation of JAK-STAT cascade | import into cell | regulation of intracellular signal transduction | cofactor transport | metabolic process | regulation of adaptive immune response | chemical homeostasis | endocytosis | heme transporter activity | organic substance metabolic process | pigment metabolic process | ion homeostasis | regulation of phosphate metabolic process | cellular iron ion homeostasis | positive regulation of cytokine-mediated signaling pathway | regulation of cell communication | transmembrane transport | regulation of immunoglobulin production | positive regulation of phosphorylation | heme transport | receptor-mediated endocytosis | hemoglobin metabolic process | cellular metal ion homeostasis | heterocycle metabolic process | positive regulation of metabolic process | positive regulation of response to interferon-gamma | transition metal ion homeostasis | cellular metabolic process | peptidase activity | positive regulation of signaling | regulation of signaling | macromolecule metabolic process | regulation of phosphorus metabolic process

GO Cellular Component

cytoplasmic vesicle | cell | cytoplasmic vesicle lumen | cytoplasm | endocytic vesicle lumen | intracellular organelle | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | membrane-enclosed lumen | blood microparticle | intracellular vesicle | endocytic vesicle | intracellular | vesicle lumen