Name: | HLA-C Antigens |
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Description: | Class I human histocompatibility (HLA) antigens encoded by a small cluster of structural genes at the C locus on chromosome 6. They have significantly lower immunogenicity than the HLA-A and -B determinants and are therefore of minor importance in donor/recipient crossmatching. Their primary role is their high-risk association with certain disease manifestations (e.g., spondylarthritis, psoriasis, multiple myeloma). |
Synonyms: |
Antigens, HLA C; HLA C Antigens; Antigens, HLA-C; HLA-C
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