QuickView for hnrnph1 (gene)

Gene Symbol:

HNRNPH1 Homo sapiens

Full name:

heterogeneous nuclear ribonucleoprotein H1

Synonyms:

HNRPH, HNRPH1, hnRNPH, heterogeneous nuclear ribonucleoprotein H, heterogeneous nuclear ribonucleoprotein H1 (H)

Genomic Location:

Chr 5: 178973786-178983276

Description:

This gene encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA. These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and trans...

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This gene encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA. These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some may shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNA and is very similar to the family member HNRPF. This gene may be associated with hereditary lymphedema type I. Alternatively spliced transcript variants have been described

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

OCT1_07 ,  CGGAARNGGCNG_UNKNOWN ,  SYATTGTG_UNKNOWN ,  GGGAGGRR_MAZ_Q6 ,  CEBP_Q2 ,  CEBPDELTA_Q6 ,  CAGGTA_AREB6_01 ,  GTGACGY_E4F1_Q6 ,  TGCGCANK_UNKNOWN ,  GTTTGTT_MIR495 ,  ATGTTAA_MIR302C ,  KCCGNSWTTT_UNKNOWN ,  NRF1_Q6 ,  HLF_01 ,  YGCGYRCGC_UNKNOWN ,  SCGGAAGY_ELK1_02 ,  ATAACCT_MIR154 ,  RCGCANGCGY_NRF1_Q6

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-132 ,  Predicted Gene Targets for miR-181 ,  Predicted Gene Targets for miR-22 ,  Predicted Gene Targets for miR-324-3p ,  Predicted Gene Targets for miR-495 ,  Predicted Gene Targets for miR-505

Cytogenetic Map:

5q35.3

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