QuickView for interleukin 34 (gene)
- Gene Symbol:
- IL34
Homo sapiens - Full name:
- interleukin 34
- Synonyms:
- C16orf77, IL-34, interleukin-34
- Genomic Location:
- Chr 16: 69237969-69252085
- Description:
-
Interleukin-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R; MIM 164770) (Lin et al., 2008 [PubMed 18467591]).
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Pan troglodytes , Bos taurus , Danio rerio , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
GATA3_01 , E4BP4_01 , GCANCTGNY_MYOD_Q6 , ATCTTGC_MIR31 , TTAYRTAA_E4BP4_01 , GATA1_04 , HEB_Q6 , WTGAAAT_UNKNOWN , TFIII_Q6 , RFX1_02
- Cytogenetic Map:
-
16q22.1
GO Molecular Function
signaling receptor binding | cytokine receptor binding | molecular function regulator | macrophage colony-stimulating factor receptor binding | protein binding | receptor regulator activity | growth factor activity | receptor ligand activity | cytokine activity
GO Biological Process
regulation of monocyte differentiation | response to cytokine | regulation of immune system process | positive regulation of developmental process | defense response | positive regulation of phosphate metabolic process | cellular process | regulation of myeloid cell differentiation | positive regulation of nitrogen compound metabolic process | regulation of myeloid leukocyte differentiation | regulation of cell differentiation | regulation of cellular process | regulation of metabolic process | positive regulation of cellular protein metabolic process | response to stimulus | positive regulation of immune system process | positive regulation of protein metabolic process | response to stress | regulation of cell proliferation | molecular function regulator | positive regulation of macrophage differentiation | regulation of signal transduction | regulation of phosphorylation | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of nitrogen compound metabolic process | cytokine-mediated signaling pathway | positive regulation of monocyte differentiation | positive regulation of cell differentiation | positive regulation of myeloid cell differentiation | cellular response to cytokine stimulus | regulation of cellular protein metabolic process | cell communication | regulation of cellular metabolic process | inflammatory response | regulation of protein metabolic process | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of signaling receptor activity | receptor regulator activity | positive regulation of protein modification process | response to organic substance | regulation of hemopoiesis | cell surface receptor signaling pathway | growth factor activity | receptor ligand activity | immune response | cytokine activity | regulation of phosphate metabolic process | regulation of cell communication | regulation of macrophage differentiation | signaling | positive regulation of phosphorylation | regulation of developmental process | innate immune response | positive regulation of metabolic process | positive regulation of myeloid leukocyte differentiation | immune system process | cellular response to organic substance | signal transduction | regulation of signaling | regulation of phosphorus metabolic process
