QuickView for interleukin-31 (gene)
- Gene Symbol:
- IL31
Homo sapiens - Full name:
- interleukin 31
- Synonyms:
- IL-31, interleukin-31
- Genomic Location:
- Chr 12: 121222530-121224699
- Description:
-
IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as ast...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
12q24.31
GO Molecular Function
signaling receptor binding | cytokine receptor binding | molecular function regulator | protein binding | receptor regulator activity | receptor ligand activity | cytokine activity
GO Biological Process
response to cytokine | cellular process | regulation of cellular process | response to stimulus | molecular function regulator | regulation of signal transduction | cytokine-mediated signaling pathway | cellular response to cytokine stimulus | cell communication | regulation of signaling receptor activity | receptor regulator activity | response to organic substance | cell surface receptor signaling pathway | receptor ligand activity | cytokine activity | regulation of cell communication | signaling | immune system process | cellular response to organic substance | signal transduction | regulation of signaling
