QuickView for intrinsic factor (gene)

Gene Symbol:

GIF Homo sapiens

Full name:

gastric intrinsic factor

Synonyms:

IF, IFMH, INF, TCN3, gastric intrinsic factor, gastric intrinsic factor (vitamin B synthesis), intrinsic factor

Genomic Location:

Chr 11: 59353322-59369550

Description:

This gene is a member of the cobalamin transport protein family. It encodes a glycoprotein secreted by parietal cells of the gastric mucosa and is required for adequate absorption of vitamin B12. Vitamin B12 is necessary for erythrocyte maturation and mutations in this gene may lead to congenital pernicious anemia.

This gene is a member of the cobalamin transport protein family. It encodes a glycoprotein secreted by parietal cells of the gastric mucosa and is required for adequate absorption of vitamin B12. Vitamin B12 is necessary for erythrocyte maturation and mutations in this gene may lead to congenital pernicious anemia.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Canis lupus familiaris ,  Pan troglodytes ,  Bos taurus ,  Gallus gallus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

STAT4_01 ,  STAT5B_01 ,  AP1FJ_Q2 ,  RAAGNYNNCTTY_UNKNOWN ,  STAT_01 ,  TTCYNRGAA_STAT5B_01 ,  AAAGGAT_MIR501

Cytogenetic Map:

11q12.1

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