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QuickView for kinesin-2 (gene)


Gene Symbol:
KIF2A Homo sapiens Homo sapiens
Full name:
kinesin family member 2A
Synonyms:
CDCBM3, HK2, KIF2, kinesin-like protein KIF2A, Kinesin, heavy chain, 2, kinesin heavy chain member 2A, kinesin-2
Genomic Location:
Chr 5: 61637746-61717967
Description:
The protein encoded by this gene is a plus end-directed motor required for normal mitotic progression. The encoded protein is required for normal spindle activity during mitosis and is necessary for normal brain development. Several transcript variants encoding different isoforms have been found for this gene.
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Gallus gallus Canis lupus familiaris Danio rerio Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: miRecords):
Cytogenetic Map:
chr 5
5q12.1





GO Molecular Function

ribonucleotide binding | nucleotide binding | microtubule motor activity | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | catalytic activity | ATP binding | cytoskeletal protein binding | anion binding | adenyl nucleotide binding | motor activity | nucleoside-triphosphatase activity | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | hydrolase activity, acting on acid anhydrides | microtubule binding | purine ribonucleotide binding | tubulin binding | adenyl ribonucleotide binding | drug binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding

GO Biological Process

microtubule cytoskeleton organization involved in mitosis | antigen processing and presentation | regulation of localization | establishment of localization | microtubule cytoskeleton organization | cell differentiation | nervous system development | microtubule-based process | cellular process | regulation of cell motility | localization | spindle assembly | regulation of cellular process | cellular component organization | mitotic spindle organization | supramolecular fiber organization | microtubule-based movement | antigen processing and presentation of exogenous peptide antigen via MHC class II | cellular component assembly | organelle assembly | system development | antigen processing and presentation of peptide antigen via MHC class II | multicellular organism development | retrograde vesicle-mediated transport, Golgi to ER | cell cycle | regulation of cell migration | vesicle-mediated transport | regulation of cellular component movement | cell division | microtubule depolymerization | cellular protein complex disassembly | regulation of locomotion | Golgi vesicle transport | antigen processing and presentation of exogenous antigen | anatomical structure development | mitotic cell cycle | nuclear division | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | cytoskeleton organization | protein depolymerization | mitotic nuclear division | microtubule polymerization or depolymerization | protein-containing complex disassembly | developmental process | organelle organization | antigen processing and presentation of peptide antigen | mitotic spindle assembly | immune system process | spindle organization | multicellular organismal process

GO Cellular Component

sperm flagellum | supramolecular fiber | centriole | intracellular membrane-bounded organelle | microtubule associated complex | microtubule organizing center | cell | nuclear lumen | nucleolus | centriolar subdistal appendage | microtubule | cytoplasm | sperm principal piece | spindle | intracellular organelle | 9+2 motile cilium | motile cilium | nuclear body | centrosome | kinesin complex | protein-containing complex | cell projection | nucleoplasm | cilium | microtubule cytoskeleton | spindle pole | spindle microtubule | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | cytoskeleton | intracellular | membrane | supramolecular complex