QuickView for ldh1 (gene)

Gene Symbol:

Ldha Mus musculus

Full name:

lactate dehydrogenase A

Synonyms:

Ldh1, Ldhm, l7R2, L-lactate dehydrogenase A chain, LDH muscle subunit, LDH-M, M-LDH, lactate dehydrogenase 1, A chain, lactate dehydrogenase A4

Genomic Location:

Chr 7: 54102583-54110996

Description:

The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to hemolytic anemia and early postimplantation death in mice. Mult...

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The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to hemolytic anemia and early postimplantation death in mice. Multiple transcript variants encoding different isoforms have been found for this gene. The mouse genome contains multiple pseudogenes of this gene.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Bos taurus ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

ATF_01 ,  CREB_01 ,  CREBP1CJUN_01 ,  CREB_Q2 ,  CREB_Q4 ,  SRF_Q6 ,  ATF_B ,  HIF1_Q5 ,  ATF3_Q6 ,  ATF1_Q6 ,  USF2_Q6 ,  HIF1_Q3 ,  MYC_Q2 ,  CREB_Q2_01 ,  CREB_Q4_01 ,  CACTGCC_MIR34A_MIR34C_MIR449 ,  TGACGTCA_ATF3_Q6 ,  TGAYRTCA_ATF3_Q6 ,  CACGTG_MYC_Q2

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-34

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