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QuickView for levonordefrin (compound)
PubChem
| Name: | Nordefrin |
|---|---|
| PubChem Compound ID: | 164739 |
| Description: | A norepinephrine derivative used as a vasoconstrictor agent. |
| Molecular formula: | C9H13NO3 |
| Molecular weight: | 183.204 g/mol |
| Synonyms: |
829-74-3; Levonordefrin; Lopac-D-5290; alpha-Methylnoradrenaline; KBio1_000315; Levonordefrin [USAN]; Neo-cobefrin; Spectrum_001642; CAS-829-74-3; (-)-alpha-(1-Aminoethyl)-3,4-dihydroxybenzyl alcohol.
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DrugBank
Identification
| Name: | Nordefrin |
|---|---|
| Name (isomeric): | DB06707 |
| Drug Type: | small molecule |
| Description: | A norepinephrine derivative used as a vasoconstrictor agent. |
| Brand: | Nordefrin |
| Category: | Vasoconstrictor Agents, Nasal Decongestants |
| CAS number: | 829-74-3 |
Pharmacology
| Indication: | Used as a topical nasal decongestant and vasoconstrictor in dentistry. |
|---|---|
| Pharmacology: | is a sympathomimetic amine used as a vasoconstrictor in local anesthetic solutions. It has pharmacologic activity similar to that of Epinephrine but it is more stable than Epinephrine. In equal concentrations, Levonordefrin is less potent than Epinephrine in raising blood pressure, and as a vasoconstrictor. |
| Mechanism of Action: | It is designed to mimic the molecular shape of adrenaline. It binds to alpha-adrenergic receptors in the nasal mucosa. Here it can, therefore, cause vasoconstriction |
Interactions
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Targets
