QuickView for mAKAP (gene)
- Gene Symbol:
- Akap6
Rattus norvegicus - Full name:
- A-kinase anchoring protein 6
- Synonyms:
- mAkap, A-kinase anchor protein 6, A kinase (PRKA) anchor protein 6, AKAP-6, PRKA6, protein kinase A-anchoring protein 6
- Genomic Location:
- Chr 6: 73013359-73354520
- Description:
-
nuclear membrane anchoring protein; involved in compartmentalizing cAMP-dependent protein kinase and other signaling molecules
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for let-7 , Predicted Gene Targets for miR-143 , Predicted Gene Targets for miR-153 , Predicted Gene Targets for miR-181 , Predicted Gene Targets for miR-185 , Predicted Gene Targets for miR-26 , Predicted Gene Targets for miR-34 , Predicted Gene Targets for miR-124a , Predicted Gene Targets for miR-124u , Predicted Gene Targets for miR-543
- miRNA binding sites
(Source: miRecords):
| Transcripts Names |
|---|
| NM_022618 |
| XM_017594344 |
| XM_017594347 |
| XM_017594346 |
| XM_017594342 |
| XM_017594343 |
| XM_017594345 |
GO Molecular Function
structural molecule activity | protein phosphatase 2A binding | adenylate cyclase binding | enzyme binding | protein membrane anchor | catalytic activity | ion channel binding | protein kinase A binding | protein kinase A regulatory subunit binding | protein binding | protein phosphatase binding | transferase activity, transferring phosphorus-containing groups | protein-containing complex scaffold activity | transferase activity | kinase activity | phosphatase binding
GO Biological Process
positive regulation of release of sequestered calcium ion into cytosol | positive regulation of striated muscle cell differentiation | regulation of muscle system process | regulation of dephosphorylation | response to cytokine | positive regulation of ion transmembrane transporter activity | regulation of cellular localization | regulation of cell development | regulation of localization | cellular protein-containing complex localization | positive regulation of striated muscle tissue development | regulation of cardiac muscle cell differentiation | positive regulation of phosphoprotein phosphatase activity | positive regulation of developmental process | regulation of phosphatase activity | regulation of heart growth | cellular chemical homeostasis | positive regulation of phosphate metabolic process | positive regulation of cation channel activity | cellular response to epinephrine stimulus | positive regulation of dephosphorylation | response to organophosphorus | cellular process | localization | cellular homeostasis | regulation of calcium-mediated signaling | regulation of cell growth involved in cardiac muscle cell development | regulation of striated muscle tissue development | positive regulation of protein kinase activity | macromolecule localization | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | regulation of cell differentiation | positive regulation of cardiac muscle hypertrophy | positive regulation of muscle cell differentiation | regulation of cellular process | positive regulation of cell growth | regulation of metabolic process | positive regulation of ryanodine-sensitive calcium-release channel activity | regulation of cytosolic calcium ion concentration | regulation of relaxation of muscle | positive regulation of cellular protein metabolic process | cellular response to organonitrogen compound | positive regulation of potassium ion transport | calcium ion homeostasis | negative regulation of lyase activity | response to stimulus | positive regulation of potassium ion transmembrane transporter activity | positive regulation of protein metabolic process | positive regulation of cation transmembrane transport | regulation of blood circulation | regulation of cardiac muscle cell contraction | positive regulation of phosphatase activity | cellular localization | regulation of delayed rectifier potassium channel activity | cellular response to organic cyclic compound | positive regulation of protein serine/threonine kinase activity | positive regulation of protein dephosphorylation | metal ion homeostasis | regulation of potassium ion transmembrane transport | regulation of membrane potential | response to nitrogen compound | regulation of calcium ion transport into cytosol | regulation of signal transduction | positive regulation of calcium ion transmembrane transport | negative regulation of catalytic activity | phosphorus metabolic process | response to purine-containing compound | positive regulation of muscle organ development | regulation of muscle contraction | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | response to epinephrine | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular ion homeostasis | positive regulation of ion transmembrane transport | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | positive regulation of intracellular signal transduction | regulation of cellular component movement | positive regulation of hydrolase activity | positive regulation of cell differentiation | positive regulation of calcium-mediated signaling | regulation of release of sequestered calcium ion into cytosol | regulation of cAMP-dependent protein kinase activity | cellular response to cytokine stimulus | regulation of cellular protein metabolic process | phosphorylation | negative regulation of adenylate cyclase activity | regulation of calcium ion transmembrane transport | regulation of cyclase activity | positive regulation of cell growth involved in cardiac muscle cell development | regulation of heart contraction | cation homeostasis | phosphate-containing compound metabolic process | regulation of potassium ion transmembrane transporter activity | regulation of striated muscle contraction | regulation of relaxation of cardiac muscle | cellular cation homeostasis | regulation of cellular metabolic process | regulation of protein kinase activity | positive regulation of transporter activity | response to catecholamine | protein-containing complex localization | regulation of cardiac muscle contraction | regulation of protein metabolic process | positive regulation of signal transduction | cellular calcium ion homeostasis | homeostatic process | regulation of protein phosphorylation | positive regulation of transport | regulation of potassium ion transport | positive regulation of molecular function | regulation of ryanodine-sensitive calcium-release channel activity | positive regulation of delayed rectifier potassium channel activity | response to monoamine | positive regulation of organ growth | positive regulation of potassium ion transmembrane transport | regulation of cardiac muscle hypertrophy | positive regulation of protein modification process | regulation of growth | response to organic substance | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum | regulation of cardiac muscle tissue development | regulation of protein dephosphorylation | regulation of kinase activity | regulation of intracellular signal transduction | metabolic process | positive regulation of cell development | positive regulation of cAMP-dependent protein kinase activity | cellular protein localization | chemical homeostasis | regulation of sequestering of calcium ion | positive regulation of ion transport | positive regulation of kinase activity | regulation of calcineurin-NFAT signaling cascade | ion homeostasis | regulation of striated muscle cell differentiation | cellular response to cAMP | regulation of phosphate metabolic process | regulation of ion transmembrane transport | positive regulation of muscle tissue development | positive regulation of calcineurin-NFAT signaling cascade | response to cAMP | regulation of adenylate cyclase activity | regulation of protein kinase A signaling | positive regulation of cardiac muscle cell differentiation | regulation of cell communication | negative regulation of molecular function | positive regulation of developmental growth | positive regulation of growth | response to organic cyclic compound | regulation of developmental growth | positive regulation of calcium ion transmembrane transporter activity | regulation of transmembrane transporter activity | protein localization | regulation of ion transmembrane transporter activity | positive regulation of phosphorylation | cellular macromolecule localization | positive regulation of calcium ion transport into cytosol | regulation of organ growth | regulation of developmental process | regulation of ion transport | regulation of phosphoprotein phosphatase activity | kinase activity | positive regulation of voltage-gated potassium channel activity | regulation of muscle cell differentiation | regulation of cell growth | regulation of calcium ion transport | regulation of transport | regulation of cation channel activity | positive regulation of heart growth | response to organonitrogen compound | cellular metal ion homeostasis | positive regulation of metabolic process | regulation of actin filament-based process | regulation of calcium ion transmembrane transporter activity | cellular metabolic process | cellular response to organic substance | positive regulation of cardiac muscle tissue development | divalent inorganic cation homeostasis | regulation of membrane repolarization | regulation of cellular component organization | positive regulation of calcium ion transport | positive regulation of signaling | cellular response to catecholamine stimulus | regulation of signaling | regulation of muscle organ development | regulation of phosphorus metabolic process
GO Cellular Component
intercalated disc | integral component of membrane | sarcoplasmic reticulum | intracellular membrane-bounded organelle | sarcolemma | organelle membrane | nuclear membrane | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | membrane microdomain | junctional sarcoplasmic reticulum membrane | cell-cell junction | cell-cell contact zone | nuclear outer membrane-endoplasmic reticulum membrane network | protein-containing complex | endomembrane system | endoplasmic reticulum membrane | plasma membrane | nuclear envelope | membrane raft | perinuclear region of cytoplasm | T-tubule | calcium channel complex | membrane-bounded organelle | sarcoplasmic reticulum membrane | nucleus | organelle | sarcoplasm | cell periphery | transmembrane transporter complex | plasma membrane raft | cation channel complex | ion channel complex | intracellular | cell junction | caveola | membrane
