QuickView for melanocortin 5 receptor (gene)
- Gene Symbol:
- MC5R
Homo sapiens - Full name:
- melanocortin 5 receptor
- Synonyms:
- MC2, melanocortin receptor 5
- Genomic Location:
- Chr 18: 13815765-13816742
- Description:
-
This gene encodes a member of the seven-pass transmembrane G protein-coupled melanocortin receptor protein family that stimulate cAMP signal transduction. The encoded protein is a receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone and is suggested to play a role in sebum generation.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
18p11.21
GO Molecular Function
transmembrane signaling receptor activity | G-protein coupled receptor activity | signaling receptor activity | hormone binding | protein binding | peptide receptor activity | G-protein coupled peptide receptor activity | melanocortin receptor activity
GO Biological Process
intracellular signal transduction | cellular process | regulation of cellular process | G-protein coupled receptor activity | response to stimulus | G-protein coupled receptor signaling pathway | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | adenylate cyclase-activating G-protein coupled receptor signaling pathway | second-messenger-mediated signaling | cell communication | cyclic-nucleotide-mediated signaling | cAMP-mediated signaling | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | signaling | G-protein coupled peptide receptor activity | melanocortin receptor activity | signal transduction
GO Cellular Component
integral component of membrane | cell | intrinsic component of membrane | plasma membrane | integral component of plasma membrane | cell periphery | intracellular | membrane | intrinsic component of plasma membrane
