QuickView for neuromedin U (gene)

Gene Symbol:

NMU Homo sapiens

Full name:

neuromedin U

Synonyms:

neuromedin-U, neuromedin U precursor-related peptide/neuromedin U preproprotein, prepro-NMU

Genomic Location:

Chr 4: 56156155-56197222

Description:

This gene encodes a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in pain, stress, immune-mediated inflammatory diseases and feeding regulation. Increased expression of this gene was observed in renal, pancreatic...

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This gene encodes a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in pain, stress, immune-mediated inflammatory diseases and feeding regulation. Increased expression of this gene was observed in renal, pancreatic and lung cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. Some of these isoforms may undergo similar processing to generate the mature peptide.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Pan troglodytes ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

RNGTGGGC_UNKNOWN ,  HMGIY_Q6 ,  MSX1_01 ,  TGATTTRY_GFI1_01

Cytogenetic Map:

4q12

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