Bookmark
Forward
QuickView for nystatin (compound)
PubChem
| Name: | Nystatin |
|---|---|
| PubChem Compound ID: | 11286230 |
| Description: | Macrolide antifungal antibiotic complex produced by Streptomyces noursei, S. aureus, and other Streptomyces species. The biologically active components of the complex are nystatin A1, A2, and A3. |
| Molecular formula: | C47H75NO17 |
| Molecular weight: | 926.095 g/mol |
| Synonyms: |
C12155; 34786-70-4; Nystatin A1
|
DrugBank
Identification
| Name: | Nystatin |
|---|---|
| Name (isomeric): | DB00646 |
| Drug Type: | small molecule |
| Description: | Macrolide antifungal antibiotic complex produced by Streptomyces noursei, S. aureus, and other Streptomyces species. The biologically active components of the complex are nystatin A1, A2, and A3. |
| Brand: | Mykacet, Nyaderm, Sodium nystatin, Nystatin, sodium salt, Mykinac, Barstatin 100, Nystatin-Triamcinolone Acetonide, nystatin dihydrate, Mycolog-Ii, Candex, Nysert, PMS Nystatin, Myco-Triacet Ii, Nystop, Nadostine, Nilstat, Korostatin, Mytrex F, Mycostatin, Pedi-Dri, Nystex, Nystaform, Nystatin sodium |
| Brand name mixture: | Mecomb Crm 0.1%(Gramicidin + Neomycin (Neomycin Sulfate) + Nystatin + Triamcinolone Acetonide), Kenacomb Ont(Gramicidin + Neomycin (Neomycin Sulfate) + Nystatin + Triamcinolone Acetonide), Lidecomb Cream(Fluocinonide + Gramicidin + Neomycin Sulfate + Nystatin), Kenacomb Cream(Gramicidin + Neomycin Sulfate + Nystatin + Triamcinolone Acetonide), S... show more » |
| Category: | Anti-Bacterial Agents, Antifungal Agents, Ionophores |
| CAS number: | 1400-61-9 |
Pharmacology
| Indication: | For treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species |
|---|---|
| Pharmacology: |
Nystatin is an antibiotic which is both fungistatic and fungicidal in vitro against a wide variety of yeasts and yeast-like fungi, including Candida albicans, C. parapsilosis, C. tropicalis, C. guilliermondi, C. pseudotropicalis, C. krusei, Torulopsis glabrata, Tricophyton rubrum, T. mentag...
show more » |
| Mechanism of Action: | Nystatin exerts its antifungal activity by binding to ergosterol found in fungal cell membranes. Binding to ergosterol causes the formation of pores in the membrane. Potassium and other cellular constituents leak from the pores causing cell death. |
| Absorption: | Nystatin is not absorbed from intact skin or mucous membrane. |
| Affected organisms: | Fungi |
Interactions
| Food interaction: |
|
|---|
Targets
