QuickView for oxysterol binding protein (gene)

Gene Symbol:

OSBP2 Homo sapiens

Full name:

oxysterol binding protein 2

Synonyms:

HLM, ORP-4, ORP4, OSBPL1, OSBPL4, oxysterol-binding protein 2, OSBP-related protein 4, oxysterol binding protein-like 1, oxysterol-binding protein-related protein 4

Genomic Location:

Chr 22: 29420793-29633811

Description:

The protein encoded by this gene contains a pleckstrin homology (PH) domain and an oxysterol-binding region. It binds oxysterols such as 7-ketocholesterol and may inhibit their cytotoxicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

The protein encoded by this gene contains a pleckstrin homology (PH) domain and an oxysterol-binding region. It binds oxysterols such as 7-ketocholesterol and may inhibit their cytotoxicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CATTGTYY_SOX9_B1 ,  EGR_Q6 ,  TGCCTTA_MIR124A ,  AGGAAGC_MIR5163P ,  SP1_Q2_01

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-124u ,  Predicted Gene Targets for miR-137 ,  Predicted Gene Targets for miR-31 ,  Predicted Gene Targets for miR-410

Cytogenetic Map:

22q12.2

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