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QuickView for plcA (gene)


Gene Symbol:
Pdia3 Mus musculus Mus musculus
Full name:
protein disulfide isomerase associated 3
Synonyms:
58kDa, ERp57, ERp60, ERp61, Erp, Grp58, PDI, PDI-Q2, PI-PLC, PLC[a], Plca, protein disulfide-isomerase A3, 58 kDa glucose-regulated protein, 58 kDa microsomal protein, ER protein 57, ER protein 60, disulfide isomerase ER-60, endoplasmic reticulum protein, endoplasmic reticulum resident protein 57, endoplasmic reticulum resident protein 60, glucose regulated protein, 58 kDa, p58, phospholipase C, alpha
Genomic Location:
Chr 2: 121239638-121264423
Orthologs:
Homo sapiens Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Bos taurus Gallus gallus Canis lupus familiaris Pan troglodytes Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_007952



GO Molecular Function

MHC protein binding | oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor | protein-disulfide reductase (glutathione) activity | isomerase activity | signaling receptor binding | hydrolase activity | catalytic activity | oxidoreductase activity, acting on a sulfur group of donors | intramolecular oxidoreductase activity | identical protein binding | disulfide oxidoreductase activity | protein binding | protein disulfide isomerase activity | MHC class I protein binding | peptide disulfide oxidoreductase activity | peptidase activity | oxidoreductase activity

GO Biological Process

response to extracellular stimulus | response to nutrient levels | response to endoplasmic reticulum stress | positive regulation of apoptotic process | proteolysis | regulation of programmed cell death | cellular response to extracellular stimulus | oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor | cellular process | cellular homeostasis | protein-disulfide reductase (glutathione) activity | regulation of cellular process | regulation of apoptotic process | cellular response to lipid | positive regulation of protein folding | response to stimulus | response to stress | cell redox homeostasis | cellular response to vitamin | cellular response to organic cyclic compound | response to vitamin D | cellular response to nutrient levels | cellular response to vitamin D | nitrogen compound metabolic process | regulation of signal transduction | oxidoreductase activity, acting on a sulfur group of donors | regulation of extrinsic apoptotic signaling pathway | cellular response to stress | response to lipid | response to nutrient | regulation of apoptotic signaling pathway | positive regulation of extrinsic apoptotic signaling pathway | cell communication | positive regulation of signal transduction | homeostatic process | disulfide oxidoreductase activity | protein metabolic process | cellular response to nutrient | response to organic substance | metabolic process | oxidation-reduction process | positive regulation of cell death | organic substance metabolic process | protein folding | response to vitamin | positive regulation of programmed cell death | regulation of cell communication | response to organic cyclic compound | peptide disulfide oxidoreductase activity | peptidase activity | cellular response to organic substance | regulation of cell death | oxidoreductase activity | positive regulation of apoptotic signaling pathway | positive regulation of signaling | regulation of signaling | macromolecule metabolic process

GO Cellular Component

secretory granule | integral component of membrane | mitochondrial intermembrane space | intracellular membrane-bounded organelle | apical plasma membrane | cytoplasmic vesicle | cell | integral component of endoplasmic reticulum membrane | smooth endoplasmic reticulum | intrinsic component of membrane | cytoplasm | acrosomal vesicle | intracellular organelle | intrinsic component of endoplasmic reticulum membrane | endoplasmic reticulum | apical part of cell | nuclear outer membrane-endoplasmic reticulum membrane network | protein-containing complex | secretory vesicle | endomembrane system | MHC class I peptide loading complex | endoplasmic reticulum membrane | plasma membrane | vesicle | mitochondrion | extracellular region | TAP complex | membrane-bounded organelle | nucleus | organelle | mitochondrial envelope | extracellular space | cell periphery | membrane-enclosed lumen | intracellular vesicle | cell surface | intracellular | myelin sheath | membrane