QuickView for polycystin 2 (gene)
- Gene Symbol:
- Pkd2
Mus musculus - Full name:
- polycystic kidney disease 2
- Synonyms:
- C030034P18Rik, PC2, TRPP2, polycystin-2, polycystic kidney disease 2 protein homolog, polycystin 2, transient receptor potential cation channel subfamily P member 2
- Genomic Location:
- Chr 5: 104888573-104934835
- Orthologs:
- Homo sapiens , Rattus norvegicus , C. elegans , Macaca mulatta , Gallus gallus , Danio rerio , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
calcium-induced calcium release activity | ligand-gated calcium channel activity | voltage-gated ion channel activity | cation binding | passive transmembrane transporter activity | enzyme binding | voltage-gated sodium channel activity | transmembrane transporter activity | ligand-gated ion channel activity | ion gated channel activity | signaling receptor binding | alpha-actinin binding | muscle alpha-actinin binding | ion channel binding | voltage-gated calcium channel activity | protein domain specific binding | cytoskeletal protein binding | ATPase binding | cation transmembrane transporter activity | transporter activity | calcium ion transmembrane transporter activity | identical protein binding | ion transmembrane transporter activity | ion binding | voltage-gated potassium channel activity | calcium-release channel activity | phosphoprotein binding | protein binding | protein homodimerization activity | potassium channel activity | metal ion transmembrane transporter activity | protein dimerization activity | voltage-gated cation channel activity | potassium ion transmembrane transporter activity | sodium ion transmembrane transporter activity | sodium channel activity | outward rectifier potassium channel activity | cation channel activity | calcium ion binding | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | intracellular ligand-gated ion channel activity | voltage-gated channel activity | channel activity | HLH domain binding | calcium channel activity | actinin binding | metal ion binding | ion channel activity | substrate-specific channel activity
GO Biological Process
positive regulation of cyclin-dependent protein serine/threonine kinase activity | positive regulation of release of sequestered calcium ion into cytosol | protein homooligomerization | regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | determination of liver left/right asymmetry | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle | detection of stimulus | positive regulation of ion transmembrane transporter activity | developmental process involved in reproduction | regulation of cellular localization | intracellular signal transduction | calcium ion transmembrane import into cytosol | cytosolic calcium ion transport | regulation of localization | regulation of cell cycle G1/S phase transition | calcium-induced calcium release activity | morphogenesis of an epithelium | ligand-gated calcium channel activity | establishment of localization | regulation of nitric oxide biosynthetic process | negative regulation of cellular process | response to metal ion | JAK-STAT cascade | response to water | cellular chemical homeostasis | regulation of G1/S transition of mitotic cell cycle | positive regulation of phosphate metabolic process | positive regulation of cation channel activity | voltage-gated ion channel activity | pattern specification process | response to organophosphorus | positive regulation of cellular biosynthetic process | cellular process | localization | cellular homeostasis | epithelial tube morphogenesis | regulation of calcium-mediated signaling | heart morphogenesis | passive transmembrane transporter activity | negative regulation of signaling | metal ion transport | negative regulation of G1/S transition of mitotic cell cycle | positive regulation of reactive oxygen species metabolic process | determination of left/right symmetry | reproductive system development | renal tubule morphogenesis | positive regulation of protein kinase activity | macromolecule localization | regulation of cell cycle | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | response to inorganic substance | establishment of localization in cell | tissue development | regulation of cellular process | regulation of metabolic process | regulation of cytosolic calcium ion concentration | voltage-gated sodium channel activity | hepaticobiliary system development | transmembrane transporter activity | positive regulation of cyclin-dependent protein kinase activity | regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity | positive regulation of cellular protein metabolic process | ligand-gated ion channel activity | epithelium development | cellular response to organonitrogen compound | cellular component organization | negative regulation of calcium-mediated signaling | calcium ion homeostasis | cellular response to metal ion | urogenital system development | calcium ion transport into cytosol | response to stimulus | ion gated channel activity | vasculature development | regulation of mitotic cell cycle phase transition | positive regulation of nitric oxide metabolic process | positive regulation of protein metabolic process | determination of heart left/right asymmetry | response to stress | positive regulation of cation transmembrane transport | regulation of cell proliferation | tube morphogenesis | regulation of cell cycle phase transition | cellular response to hydrostatic pressure | negative regulation of transporter activity | reproduction | cellular response to inorganic substance | cellular localization | divalent metal ion transport | cardiovascular system development | negative regulation of transport | cellular response to organic cyclic compound | positive regulation of protein serine/threonine kinase activity | positive regulation of RNA biosynthetic process | cellular component assembly | kidney development | embryo development | negative regulation of calcium ion transmembrane transport | negative regulation of transmembrane transport | metal ion homeostasis | embryonic placenta development | blood vessel development | regulation of nucleic acid-templated transcription | voltage-gated calcium channel activity | detection of abiotic stimulus | regulation of neurotransmitter levels | response to nitrogen compound | regulation of calcium ion transport into cytosol | positive regulation of reactive oxygen species biosynthetic process | system development | regulation of cyclin-dependent protein serine/threonine kinase activity | reproductive process | regulation of signal transduction | negative regulation of mitotic cell cycle phase transition | positive regulation of calcium ion transmembrane transport | multicellular organism development | calcium ion transmembrane transport | response to purine-containing compound | protein complex oligomerization | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | ion transmembrane transport | positive regulation of cell cycle | determination of bilateral symmetry | regulation of gene expression | cellular response to stress | cell cycle | sodium ion transport | cation transmembrane transporter activity | embryonic heart tube morphogenesis | regulation of cell cycle arrest | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular ion homeostasis | monovalent inorganic cation transport | animal organ morphogenesis | liver development | positive regulation of ion transmembrane transport | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | placenta blood vessel development | negative regulation of release of sequestered calcium ion into cytosol | cytoplasmic sequestering of protein | negative regulation of DNA-binding transcription factor activity | positive regulation of intracellular signal transduction | cellular response to fluid shear stress | cellular potassium ion transport | regulation of transcription by RNA polymerase II | protein homotetramerization | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | potassium ion transport | second-messenger-mediated signaling | positive regulation of calcium-mediated signaling | regulation of release of sequestered calcium ion into cytosol | negative regulation of ion transmembrane transport | negative regulation of calcium ion transmembrane transporter activity | response to osmotic stress | negative regulation of sequestering of calcium ion | regulation of cellular protein metabolic process | cytoplasmic sequestering of transcription factor | negative regulation of ion transport | regulation of calcium ion transmembrane transport | protein tetramerization | heart looping | cation homeostasis | maintenance of protein location | chordate embryonic development | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | negative regulation of cation channel activity | renal tubule development | voltage-gated potassium channel activity | positive regulation of transporter activity | positive regulation of sequestering of calcium ion | negative regulation of calcium ion transport | regulation of protein metabolic process | positive regulation of signal transduction | heart development | cellular calcium ion homeostasis | homeostatic process | calcium-release channel activity | regulation of protein phosphorylation | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | renal system development | positive regulation of transport | negative regulation of calcium ion transport into cytosol | embryonic morphogenesis | regulation of mitotic cell cycle | positive regulation of molecular function | release of sequestered calcium ion into cytosol | calcium-mediated signaling | regulation of ryanodine-sensitive calcium-release channel activity | positive regulation of cell cycle arrest | cation transmembrane transport | embryonic organ morphogenesis | potassium channel activity | protein-containing complex assembly | positive regulation of protein modification process | cellular response to calcium ion | response to organic substance | gland development | tissue morphogenesis | cell cycle arrest | regulation of kinase activity | response to mechanical stimulus | metal ion transmembrane transporter activity | cellular response to osmotic stress | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | embryonic heart tube development | anatomical structure development | detection of nodal flow | voltage-gated cation channel activity | potassium ion transmembrane transporter activity | regulation of RNA biosynthetic process | embryonic organ development | negative regulation of mitotic cell cycle | chemical homeostasis | calcium ion transport | sodium ion transmembrane transport | negative regulation of ion transmembrane transporter activity | regulation of sequestering of calcium ion | animal organ development | positive regulation of ion transport | positive regulation of kinase activity | ion homeostasis | sodium ion transmembrane transporter activity | cellular response to cAMP | regulation of phosphate metabolic process | inorganic cation transmembrane transport | regulation of ion transmembrane transport | sodium channel activity | detection of mechanical stimulus | outward rectifier potassium channel activity | response to cAMP | regulation of reactive oxygen species biosynthetic process | cation channel activity | negative regulation of cell cycle | regulation of calcium ion import | response to fluid shear stress | regulation of cell communication | negative regulation of cell cycle G1/S phase transition | negative regulation of molecular function | negative regulation of signal transduction | transmembrane transport | signaling | inorganic cation transmembrane transporter activity | regulation of transcription, DNA-templated | response to organic cyclic compound | monovalent inorganic cation transmembrane transporter activity | intracellular ligand-gated ion channel activity | positive regulation of calcium ion transmembrane transporter activity | regulation of transmembrane transporter activity | protein localization | regulation of ion transmembrane transporter activity | positive regulation of phosphorylation | response to hydrostatic pressure | voltage-gated channel activity | anatomical structure morphogenesis | cation transport | channel activity | positive regulation of calcium ion transport into cytosol | reproductive structure development | regulation of ion transport | developmental process | calcium channel activity | negative regulation of ryanodine-sensitive calcium-release channel activity | positive regulation of cell cycle process | regulation of calcium ion transport | tube development | regulation of transport | positive regulation of transcription, DNA-templated | regulation of reactive oxygen species metabolic process | regulation of cation channel activity | positive regulation of nucleic acid-templated transcription | response to organonitrogen compound | potassium ion transmembrane transport | cellular metal ion homeostasis | positive regulation of transcription by RNA polymerase II | positive regulation of nitric oxide biosynthetic process | response to calcium ion | ion channel activity | in utero embryonic development | cellular response to water stimulus | positive regulation of metabolic process | regulation of calcium ion transmembrane transporter activity | ion transport | negative regulation of cell cycle process | placenta development | cellular response to organic substance | circulatory system development | divalent inorganic cation homeostasis | substrate-specific channel activity | positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity | positive regulation of calcium ion transport | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
supramolecular fiber | non-motile cilium | integral component of membrane | basal plasma membrane | intracellular membrane-bounded organelle | basal cortex | ciliary membrane | organelle membrane | cell projection membrane | microtubule organizing center | cytoplasmic vesicle | basal part of cell | cell | integral component of endoplasmic reticulum membrane | cytoplasmic side of membrane | intrinsic component of membrane | lamellipodium | cytoplasm | spindle | intracellular organelle | actin cytoskeleton | intrinsic component of endoplasmic reticulum membrane | endoplasmic reticulum | motile cilium | cell-cell junction | nuclear outer membrane-endoplasmic reticulum membrane network | protein-containing complex | cell projection | integral component of lumenal side of endoplasmic reticulum membrane | endomembrane system | endoplasmic reticulum membrane | plasma membrane | cell leading edge | cytoplasmic side of endoplasmic reticulum membrane | cilium | vesicle | microtubule cytoskeleton | cytoplasmic region | filamentous actin | integral component of plasma membrane | cell cortex region | cell cortex | membrane-bounded organelle | organelle | cell periphery | basolateral plasma membrane | integral component of cytoplasmic side of endoplasmic reticulum membrane | intracellular vesicle | actin filament | cytoskeleton | intracellular | cell junction | mitotic spindle | membrane | supramolecular complex | ciliary basal body | intrinsic component of plasma membrane | polycystin complex
