Correlation Engine 2.0
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Gene Symbol:
AMACR Homo sapiens Homo sapiens
Full name:
alpha-methylacyl-CoA racemase
AMACRD, CBAS4, P504S, RACE, RM, alpha-methylacyl-CoA racemase, 2-methylacyl-CoA racemase
Genomic Location:
Chr 5: 34023652-34043963
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutation...
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Gallus gallus Pan troglodytes Bos taurus Danio rerio Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 5

GO Molecular Function

racemase and epimerase activity | isomerase activity | signaling receptor binding | catalytic activity | protein binding | alpha-methylacyl-CoA racemase activity

GO Biological Process

peroxisome organization | establishment of localization | fatty acid beta-oxidation | bile acid biosynthetic process | intracellular transport | cellular process | organic substance catabolic process | localization | protein transport | protein targeting to peroxisome | macromolecule localization | establishment of localization in cell | catabolic process | organic cyclic compound metabolic process | steroid biosynthetic process | cellular component organization | cellular lipid metabolic process | monocarboxylic acid metabolic process | carboxylic acid catabolic process | intracellular protein transport | cellular localization | fatty acid catabolic process | cellular biosynthetic process | organic hydroxy compound metabolic process | lipid metabolic process | organic substance transport | small molecule metabolic process | peptide transport | protein localization to organelle | biosynthetic process | lipid biosynthetic process | establishment of protein localization to peroxisome | cellular lipid catabolic process | lipid modification | carboxylic acid metabolic process | bile acid metabolic process | establishment of protein localization to organelle | metabolic process | oxidation-reduction process | cellular protein localization | amide transport | lipid catabolic process | organic substance metabolic process | fatty acid metabolic process | establishment of protein localization | lipid oxidation | steroid metabolic process | protein localization | organic acid metabolic process | cellular macromolecule localization | fatty acid beta-oxidation using acyl-CoA oxidase | organelle organization | fatty acid oxidation | protein targeting | cellular metabolic process

GO Cellular Component

peroxisomal matrix | intracellular membrane-bounded organelle | peroxisome | cell | cytoplasm | intracellular organelle | plasma membrane | mitochondrion | membrane-bounded organelle | organelle | cell periphery | membrane-enclosed lumen | cytosol | intracellular | membrane