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QuickView for ryanodine receptor 3 (gene)


Gene Symbol:
RYR3 Homo sapiens Homo sapiens
Full name:
ryanodine receptor 3
Synonyms:
RYR-3, ryanodine receptor 3, brain ryanodine receptor-calcium release channel, brain-type ryanodine receptor, type 3 ryanodine receptor
Genomic Location:
Chr 15: 31390469-31945595
Description:
The protein encoded by this gene is a ryanodine receptor, which functions to release calcium from intracellular storage for use in many cellular processes. For example, the encoded protein is involved in skeletal muscle contraction by releasing calcium from the sarcoplasmic reticulum followed by depolarization of T-tubules. Two transcript variants ...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 15
15q13.3-q14





GO Molecular Function

calcium-induced calcium release activity | ligand-gated calcium channel activity | cation binding | passive transmembrane transporter activity | transmembrane transporter activity | ligand-gated ion channel activity | ion gated channel activity | ryanodine-sensitive calcium-release channel activity | cation transmembrane transporter activity | transporter activity | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | ion binding | calcium-release channel activity | protein binding | metal ion transmembrane transporter activity | cation channel activity | calcium ion binding | inorganic cation transmembrane transporter activity | intracellular ligand-gated ion channel activity | channel activity | calcium channel activity | calmodulin binding | metal ion binding | ion channel activity | substrate-specific channel activity

GO Biological Process

response to extracellular stimulus | protein homooligomerization | response to nutrient levels | response to ATP | intracellular signal transduction | calcium ion transmembrane import into cytosol | cytosolic calcium ion transport | regulation of localization | calcium-induced calcium release activity | ligand-gated calcium channel activity | establishment of localization | negative regulation of cellular process | response to metal ion | cellular response to extracellular stimulus | response to drug | cellular response to caffeine | cellular chemical homeostasis | response to organophosphorus | cellular process | response to magnesium ion | localization | cellular homeostasis | passive transmembrane transporter activity | metal ion transport | response to inorganic substance | establishment of localization in cell | regulation of cellular process | regulation of cytosolic calcium ion concentration | transmembrane transporter activity | ligand-gated ion channel activity | cellular response to organonitrogen compound | cellular component organization | calcium ion homeostasis | cellular response to metal ion | calcium ion transport into cytosol | response to stimulus | ion gated channel activity | cellular response to xenobiotic stimulus | ryanodine-sensitive calcium-release channel activity | regulation of blood circulation | cellular response to inorganic substance | cellular localization | divalent metal ion transport | cellular response to organic cyclic compound | cellular component assembly | metal ion homeostasis | response to nitrogen compound | cellular response to nutrient levels | calcium ion transmembrane transport | response to purine-containing compound | protein complex oligomerization | ion transmembrane transport | cellular response to ATP | cation transmembrane transporter activity | cellular ion homeostasis | positive regulation of cytosolic calcium ion concentration | protein homotetramerization | response to nutrient | cellular response to alkaloid | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | second-messenger-mediated signaling | negative regulation of sequestering of calcium ion | protein tetramerization | response to xenobiotic stimulus | regulation of heart contraction | cation homeostasis | cellular response to drug | cellular cation homeostasis | cell communication | cellular calcium ion homeostasis | homeostatic process | calcium-release channel activity | release of sequestered calcium ion into cytosol | calcium-mediated signaling | cation transmembrane transport | protein-containing complex assembly | cellular response to nutrient | cellular response to calcium ion | response to organic substance | cellular response to purine-containing compound | metal ion transmembrane transporter activity | chemical homeostasis | calcium ion transport | response to caffeine | regulation of sequestering of calcium ion | ion homeostasis | inorganic cation transmembrane transport | response to alkaloid | cation channel activity | transmembrane transport | signaling | inorganic cation transmembrane transporter activity | response to organic cyclic compound | intracellular ligand-gated ion channel activity | cation transport | channel activity | negative regulation of cytosolic calcium ion concentration | calcium channel activity | regulation of cardiac conduction | response to organonitrogen compound | cellular metal ion homeostasis | response to calcium ion | ion channel activity | ion transport | cellular response to organic substance | divalent inorganic cation homeostasis | substrate-specific channel activity | signal transduction | regulation of signaling | cellular response to magnesium ion

GO Cellular Component

supramolecular fiber | integral component of membrane | sarcoplasmic reticulum | intracellular membrane-bounded organelle | sarcolemma | organelle membrane | sarcomere | cytoplasmic vesicle | cell | smooth endoplasmic reticulum | intrinsic component of membrane | myofibril | cytoplasm | intracellular organelle | endoplasmic reticulum | contractile fiber | nuclear outer membrane-endoplasmic reticulum membrane network | protein-containing complex | endomembrane system | endoplasmic reticulum membrane | plasma membrane | vesicle | perinuclear region of cytoplasm | calcium channel complex | membrane-bounded organelle | sarcoplasmic reticulum membrane | organelle | I band | vesicle membrane | sarcoplasm | cell periphery | transmembrane transporter complex | cation channel complex | ion channel complex | Z disc | intracellular vesicle | intracellular | membrane | supramolecular complex | cytoplasmic vesicle membrane