QuickView for secretin (gene)

Gene Symbol:

SCT Homo sapiens

Full name:

secretin

Synonyms:

secretin, prepro-secretin

Genomic Location:

Chr 11: 616313-617173

Description:

This gene encodes a member of the glucagon family of peptides. The encoded preproprotein is secreted by endocrine S cells in the proximal small intestinal mucosa as a prohormone, then proteolytically processed to generate the mature peptide hormone. The release of this active peptide hormone is stimulated by either fatty acids or acidic pH in the d...

View Full Description

This gene encodes a member of the glucagon family of peptides. The encoded preproprotein is secreted by endocrine S cells in the proximal small intestinal mucosa as a prohormone, then proteolytically processed to generate the mature peptide hormone. The release of this active peptide hormone is stimulated by either fatty acids or acidic pH in the duodenum. This hormone stimulates the secretion of bile and bicarbonate in the duodenum, pancreatic and biliary ducts.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Canis lupus familiaris ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

PBX1_01 ,  TGACCTY_ERR1_Q2 ,  HNF4_01 ,  GGGYGTGNY_UNKNOWN ,  T3R_Q6 ,  ER_Q6_02 ,  CAGCTG_AP4_Q5

Cytogenetic Map:

11p15.5

search → result