QuickView for secretogranin II (gene)

Gene Symbol:

SCG2 Homo sapiens

Full name:

secretogranin II

Synonyms:

CHGC, EM66, SN, SgII, secretogranin-2, chromogranin-C, secretoneurin

Genomic Location:

Chr 2: 224169902-224175365

Description:

The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce th...

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The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  E12_Q6 ,  POU6F1_01 ,  MYOD_Q6_01 ,  MYOD_01 ,  CREBP1CJUN_01 ,  CREB_Q4_01 ,  CTTTGA_LEF1_Q2 ,  CREB_Q4 ,  TGAYRTCA_ATF3_Q6 ,  ATF_B ,  CREBP1_Q2 ,  AGCATTA_MIR155 ,  RGAANNTTC_HSF1_01 ,  GTGACGY_E4F1_Q6 ,  YYCATTCAWW_UNKNOWN ,  FREAC3_01 ,  ATF_01 ,  CAGGTG_E12_Q6 ,  HSF1_01 ,  MYOD_Q6 ,  CREB_02 ,  ATF3_Q6 ,  E4F1_Q6 ,  ATF1_Q6 ,  STAT5A_04 ,  CREB_Q2 ,  TGACGTCA_ATF3_Q6 ,  AACTTT_UNKNOWN ,  CREB_Q2_01 ,  CEBPGAMMA_Q6 ,  CREB_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-155 ,  Predicted Gene Targets for miR-374 ,  Predicted Gene Targets for miR-495 ,  Predicted Gene Targets for miR-543

Cytogenetic Map:

2q36.1

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