QuickView for sedoheptulokinase (gene)

Gene Symbol:

SHPK Homo sapiens

Full name:

sedoheptulokinase

Synonyms:

CARKL, SHK, sedoheptulokinase, carbohydrate kinase-like protein

Genomic Location:

Chr 17: 3458305-3486365

Description:

The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or c...

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The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TCANNTGAY_SREBP1_01 ,  CAGGTG_E12_Q6 ,  USF_02

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-103

Cytogenetic Map:

17p13.2

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