QuickView for set1A (gene)

Gene Symbol:

SETD1A Homo sapiens

Full name:

SET domain containing 1A

Synonyms:

KMT2F, Set1, Set1A, histone-lysine N-methyltransferase SETD1A, SET domain-containing protein 1A, hSET1A, lysine N-methyltransferase 2F, set1/Ash2 histone methyltransferase complex subunit SET1

Genomic Location:

Chr 16: 30876116-30903482

Description:

The protein encoded by this gene is a component of a histone methyltransferase (HMT) complex that produces mono-, di-, and trimethylated histone H3 at Lys4. Trimethylation of histone H3 at lysine 4 (H3K4me3) is a chromatin modification known to generally mark the transcription start sites of active genes. The protein contains SET domains, a RNA rec...

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The protein encoded by this gene is a component of a histone methyltransferase (HMT) complex that produces mono-, di-, and trimethylated histone H3 at Lys4. Trimethylation of histone H3 at lysine 4 (H3K4me3) is a chromatin modification known to generally mark the transcription start sites of active genes. The protein contains SET domains, a RNA recognition motif domain and is a member of the class V-like SAM-binding methyltransferase superfamily.

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Orthologs:

Mus musculus ,  C. elegans ,  Macaca mulatta ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TTTGTAG_MIR520D ,  ACTTTAT_MIR1425P

Cytogenetic Map:

16p11.2

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