QuickView for signal transducer and activator of transcription 1 (gene)
- Gene Symbol:
- Stat1
Mus musculus - Full name:
- signal transducer and activator of transcription 1
- Synonyms:
- 2010005J02Rik, AA408197, signal transducer and activator of transcription 1
- Genomic Location:
- Chr 1: 52176282-52218707
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
| Transcripts Names |
|---|
| NM_009283 |
| NM_001205313 |
| NM_001205314 |
| XM_017319464 |
| XM_006495811 |
| NM_001357627 |
| XM_017319463 |
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | core promoter binding | protein phosphatase 2A binding | repressing transcription factor binding | hormone receptor binding | proximal promoter sequence-specific DNA binding | CCR chemokine receptor binding | enzyme binding | nucleic acid binding | signaling receptor binding | cytokine receptor binding | chromatin binding | RNA polymerase II core promoter sequence-specific DNA binding | ubiquitin-like protein ligase binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | promoter-specific chromatin binding | identical protein binding | nuclear hormone receptor binding | chemokine receptor binding | organic cyclic compound binding | tumor necrosis factor receptor binding | transcription regulatory region sequence-specific DNA binding | protein binding | histone acetyltransferase binding | protein homodimerization activity | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | DNA-binding transcription factor activity | protein phosphatase binding | transcription factor binding | protein dimerization activity | G-protein coupled receptor binding | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | histone binding | core promoter sequence-specific DNA binding | CCR5 chemokine receptor binding | phosphatase binding | tumor necrosis factor receptor superfamily binding | transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding | heterocyclic compound binding
GO Biological Process
RNA metabolic process | positive regulation of smooth muscle cell proliferation | response to extracellular stimulus | positive regulation of erythrocyte differentiation | positive regulation of macromolecule biosynthetic process | regulation of cysteine-type endopeptidase activity | response to virus | response to nutrient levels | macrophage derived foam cell differentiation | response to cytokine | response to lipopolysaccharide | intracellular signal transduction | positive regulation of apoptotic process | regulation of programmed cell death | cellular response to type I interferon | defense response to other organism | regulation of immune system process | response to hormone | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | positive regulation of developmental process | cellular response to tumor necrosis factor | cell differentiation | JAK-STAT cascade | defense response | response to drug | response to organophosphorus | positive regulation of cellular biosynthetic process | cellular process | response to exogenous dsRNA | response to type I interferon | regulation of syncytium formation by plasma membrane fusion | negative regulation of signaling | positive regulation of defense response to virus by host | regulation of defense response to virus | regulation of proteolysis | positive regulation of catalytic activity | regulation of myeloid cell differentiation | positive regulation of nitrogen compound metabolic process | response to peptide hormone | tissue development | regulation of cell differentiation | regulation of angiogenesis | regulation of cellular process | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | interferon-gamma-mediated signaling pathway | cellular response to molecule of bacterial origin | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | RNA biosynthetic process | epithelium development | cellular response to organonitrogen compound | cellular aromatic compound metabolic process | urogenital system development | cellular response to interferon-gamma | regulation of type I interferon production | regulation of vasculature development | response to stimulus | negative regulation by virus of viral protein levels in host cell | positive regulation of immune system process | positive regulation of protein metabolic process | positive regulation of peptidase activity | response to stress | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | response to interferon-beta | negative regulation of angiogenesis | response to peptide | positive regulation of cysteine-type endopeptidase activity | positive regulation of proteolysis | response to molecule of bacterial origin | cellular nitrogen compound metabolic process | cellular response to organic cyclic compound | blood circulation | positive regulation of RNA biosynthetic process | cellular biosynthetic process | regulation of nucleic acid-templated transcription | response to nitrogen compound | cellular response to hormone stimulus | response to external biotic stimulus | system development | nitrogen compound metabolic process | regulation of signal transduction | multicellular organism development | cellular response to peptide hormone stimulus | regulation of peptidase activity | response to purine-containing compound | response to dsRNA | cellular response to insulin stimulus | regulation of catalytic activity | regulation of gene expression | response to lipid | cellular response to peptide | negative regulation of macrophage fusion | positive regulation of cellular metabolic process | defense response to virus | regulation of nitrogen compound metabolic process | regulation of cysteine-type endopeptidase activity involved in apoptotic process | cytokine-mediated signaling pathway | regulation of transcription by RNA polymerase II | response to nutrient | positive regulation of hydrolase activity | positive regulation of cell differentiation | negative regulation of viral process | positive regulation of myeloid cell differentiation | cellular response to cytokine stimulus | biosynthetic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | positive regulation of endopeptidase activity | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | response to bacterium | cell communication | regulation of cellular metabolic process | renal tubule development | regulation of protein metabolic process | homeostatic process | positive regulation of cell proliferation | regulation of RNA metabolic process | renal system development | lipopolysaccharide-mediated signaling pathway | regulation of viral process | positive regulation of interferon-alpha production | positive regulation of molecular function | negative regulation of epithelial cell proliferation | DNA-binding transcription factor activity | response to organic substance | regulation of hemopoiesis | response to mechanical stimulus | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | response to insulin | anatomical structure development | cell surface receptor signaling pathway | metabolic process | negative regulation of I-kappaB kinase/NF-kappaB signaling | activation of cysteine-type endopeptidase activity involved in apoptotic process | regulation of RNA biosynthetic process | regulation of erythrocyte differentiation | negative regulation of endothelial cell proliferation | chemical homeostasis | positive regulation of cell death | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | immune response | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of syncytium formation by plasma membrane fusion | regulation of endothelial cell proliferation | gene expression | positive regulation of programmed cell death | tumor necrosis factor-mediated signaling pathway | regulation by virus of viral protein levels in host cell | transcription, DNA-templated | response to interferon-gamma | positive regulation of cytokine production | response to cAMP | type I interferon signaling pathway | foam cell differentiation | regulation of cell communication | negative regulation of signal transduction | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | regulation of epithelial cell proliferation | regulation of cytokine production | regulation of endopeptidase activity | cellular macromolecule biosynthetic process | cellular response to interferon-beta | response to biotic stimulus | regulation of developmental process | developmental process | tube development | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | innate immune response | negative regulation of vasculature development | positive regulation of nucleic acid-templated transcription | response to organonitrogen compound | positive regulation of transcription by RNA polymerase II | regulation of defense response to virus by host | heterocycle metabolic process | transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding | positive regulation of metabolic process | immune system process | cellular metabolic process | response to tumor necrosis factor | cellular response to organic substance | regulation of cell death | regulation of smooth muscle cell proliferation | positive regulation of type I interferon production | regulation of I-kappaB kinase/NF-kappaB signaling | regulation of cellular component organization | response to other organism | signal transduction | regulation of signaling | positive regulation of nitric-oxide synthase biosynthetic process | positive regulation of gene expression | cellular response to lipopolysaccharide | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
chromosome | dendrite | intracellular membrane-bounded organelle | neuron projection | somatodendritic compartment | cell | nuclear lumen | nucleolus | cytoplasm | intracellular organelle | dendritic tree | protein-containing complex | cell projection | nucleoplasm | chromatin | nuclear chromosome | perinuclear region of cytoplasm | membrane-bounded organelle | nucleus | organelle | axon | membrane-enclosed lumen | nuclear chromatin | cytosol | intracellular
