QuickView for stathmin-2 (gene)

Gene Symbol:

STMN2 Homo sapiens

Full name:

stathmin 2

Synonyms:

SCG10, SCGN10, stathmin-2, neuron-specific growth-associated protein, neuronal growth-associated protein (silencer element), stathmin-like 2, superior cervical ganglia, neural specific 10, superior cervical ganglion-10 protein

Genomic Location:

Chr 8: 80685935-80739792

Description:

This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down's syndrome and A...

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This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 6.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  GATTGGY_NFY_Q6_01 ,  OCT1_05 ,  STAT4_01 ,  TGANTCA_AP1_C ,  TTANTCA_UNKNOWN ,  TGANNYRGCA_TCF11MAFG_01 ,  GCANCTGNY_MYOD_Q6 ,  YATTNATC_UNKNOWN ,  HNF4_DR1_Q3 ,  WTGAAAT_UNKNOWN ,  NRSF_01 ,  GGGAGGRR_MAZ_Q6 ,  CDP_01 ,  TATAAA_TATA_01 ,  CDPCR3HD_01 ,  NFE2_01 ,  TGTATGA_MIR4853P ,  PAX4_02 ,  NFY_Q6_01 ,  CAGGTG_E12_Q6 ,  DR1_Q3 ,  NKX62_Q2 ,  BACH2_01 ,  CDPCR1_01 ,  GGGCGGR_SP1_Q6 ,  POU1F1_Q6 ,  OCT1_06 ,  ACTWSNACTNY_UNKNOWN ,  RNGTGGGC_UNKNOWN ,  TAATTA_CHX10_01 ,  TTGTTT_FOXO4_01 ,  HEN1_02 ,  COUP_DR1_Q6 ,  CTGCAGY_UNKNOWN ,  CTTTGT_LEF1_Q2 ,  CAGCTG_AP4_Q5 ,  BRN2_01 ,  PAX4_03 ,  PAX2_02 ,  RYTAAWNNNTGAY_UNKNOWN ,  TATTATA_MIR374 ,  GGGTGGRR_PAX4_03 ,  LMO2COM_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-34b ,  Predicted Gene Targets for miR-369-3p ,  Predicted Gene Targets for miR-374 ,  Predicted Gene Targets for miR-485-3p

Cytogenetic Map:

8q21.13

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