QuickView for synaptojanin 1 (gene)

Gene Symbol:

SYNJ1 Homo sapiens

Full name:

synaptojanin 1

Synonyms:

EIEE53, INPP5G, PARK20, synaptojanin-1, inositol 5'-phosphatase (synaptojanin 1), inositol polyphosphate-5-phosphatase G, phosphoinositide 5-phosphatase, synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1, synaptojanin-1, polyphosphoinositide phosphatase

Genomic Location:

Chr 21: 32922944-33022148

Description:

This gene encodes a phosphoinositide phosphatase that regulates levels of membrane phosphatidylinositol-4,5-bisphosphate. As such, expression of this enzyme may affect synaptic transmission and membrane trafficking. Multiple transcript variants encoding different isoforms have been found for this gene.

This gene encodes a phosphoinositide phosphatase that regulates levels of membrane phosphatidylinositol-4,5-bisphosphate. As such, expression of this enzyme may affect synaptic transmission and membrane trafficking. Multiple transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Bos taurus ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CACTGCC_MIR34A_MIR34C_MIR449 ,  CEBPA_01 ,  ACTTTAT_MIR1425P ,  GGGCATT_MIR365 ,  WHN_B ,  GTGCAAT_MIR25_MIR32_MIR92_MIR363_MIR367 ,  GGGAGGRR_MAZ_Q6 ,  CEBP_Q2 ,  RGAANNTTC_HSF1_01 ,  CATTTCA_MIR203 ,  GTGACGY_E4F1_Q6 ,  GGATTA_PITX2_Q2 ,  TGCACTG_MIR148A_MIR152_MIR148B ,  YGCANTGCR_UNKNOWN ,  ATGCTGC_MIR103_MIR107 ,  ACCAAAG_MIR9 ,  GGGCGGR_SP1_Q6 ,  CEBPB_02 ,  LMO2COM_02 ,  GCGNNANTTCC_UNKNOWN ,  MGGAAGTG_GABP_B ,  RNGTGGGC_UNKNOWN ,  AATGTGA_MIR23A_MIR23B ,  SCGGAAGY_ELK1_02 ,  CAGTATT_MIR200B_MIR200C_MIR429 ,  GATA1_05 ,  PAX5_01 ,  AAAGGAT_MIR501 ,  TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497 ,  GTTAAAG_MIR302B ,  ACATATC_MIR190 ,  AAGCACA_MIR218

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-103 ,  Predicted Gene Targets for miR-142-5p ,  Predicted Gene Targets for miR-148 ,  Predicted Gene Targets for miR-15 ,  Predicted Gene Targets for miR-153 ,  Predicted Gene Targets for miR-190 ,  Predicted Gene Targets for miR-200b ,  Predicted Gene Targets for miR-218 ,  Predicted Gene Targets for miR-23 ,  Predicted Gene Targets for miR-25 ,  Predicted Gene Targets for miR-323 ,  Predicted Gene Targets for miR-34 ,  Predicted Gene Targets for miR-365 ,  Predicted Gene Targets for miR-448 ,  Predicted Gene Targets for miR-9 ,  Predicted Gene Targets for miR-203 ,  Predicted Gene Targets for miR-378

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Cytogenetic Map:

21q22.11

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